Common grade 3/4 toxicities
| Toxicity . | BEACOPP 1-4, % (N = 98) . | BEACOPP 5-8, % (N = 24) . | COPP/ABV 1-2, % (N = 38) . | ABVD 1-2, % (N = 34) . |
|---|---|---|---|---|
| Neutropenia | 83 | 96 | 95 | 88 |
| Anemia | 79 | 92 | 39 | 32 |
| Thrombocytopenia | 62 | 83 | 18 | 6 |
| Febrile neutropenia (fever of unknown origin) | 34 | 25 | 42 | 18 |
| Infection | 35 | 25 | 37 | 15 |
| Stomatitis/pharyngitis | 15 | 4 | 8 | 0 |
| Pulmonary (dyspnea, DLCO, hypoxia) | 8 | 8 | 3 | 6 |
| Peripheral neuropathy | 4 | 4 | 8 | 0 |
| Nausea/vomiting | 3 | 4 | 3 | 3 |
| Allergic reaction/hypersensitivity | 7 | 0 | 0 | 0 |
| Toxicity . | BEACOPP 1-4, % (N = 98) . | BEACOPP 5-8, % (N = 24) . | COPP/ABV 1-2, % (N = 38) . | ABVD 1-2, % (N = 34) . |
|---|---|---|---|---|
| Neutropenia | 83 | 96 | 95 | 88 |
| Anemia | 79 | 92 | 39 | 32 |
| Thrombocytopenia | 62 | 83 | 18 | 6 |
| Febrile neutropenia (fever of unknown origin) | 34 | 25 | 42 | 18 |
| Infection | 35 | 25 | 37 | 15 |
| Stomatitis/pharyngitis | 15 | 4 | 8 | 0 |
| Pulmonary (dyspnea, DLCO, hypoxia) | 8 | 8 | 3 | 6 |
| Peripheral neuropathy | 4 | 4 | 8 | 0 |
| Nausea/vomiting | 3 | 4 | 3 | 3 |
| Allergic reaction/hypersensitivity | 7 | 0 | 0 | 0 |
DLCO indicates diffusing capacity of the lung for carbon monoxide.