Recurrence rates of venous thrombosis in men and women
| . | Overall venous thrombosis* . | Unprovoked venous thrombosis† . | ||
|---|---|---|---|---|
| Women . | Men . | Women . | Men . | |
| No. of subjects | 523 | 293 | 122 | 207 |
| No. of recurrences | 198 | 139 | 46 | 90 |
| Mean age at onset of recurrence, y | 40 | 48‡ | 49 | 50§ |
| Observation period, y | 3896 | 1499 | 615 | 998 |
| Annual incidence, % (95% CI) | 5.1 (4.4-5.8) | 9.3 (7.8-10.9) | 7.5 (5.5-10.0) | 9.0 (7.3-11.1) |
| Relative risk (95% CI) | Reference | 1.7 (1.4-2.1) | Reference | 1.2 (0.8-1.7) |
| Relative risk adjusted for | ||||
| Antithrombin deficiency | Reference | 1.7 (1.3-2.1) | Reference | 1.2 (0.8-1.8) |
| Protein C deficiency | Reference | 1.7 (1.3-2.1) | Reference | 1.4 (0.9-2.1) |
| Protein S deficiency | Reference | 1.6 (1.3-2.1) | Reference | 1.3 (0.8-2.0) |
| FV Leiden | Reference | 1.7 (1.3-2.1) | Reference | 1.2 (0.8-1.7) |
| FVIII more than 150 IU/dL | Reference | 1.6 (1.3-2.0) | Reference | 1.2 (0.8-1.7) |
| Prothrombin 20210G>A | Reference | 1.6 (1.3-2.0) | Reference | 1.2 (0.8-1.7) |
| . | Overall venous thrombosis* . | Unprovoked venous thrombosis† . | ||
|---|---|---|---|---|
| Women . | Men . | Women . | Men . | |
| No. of subjects | 523 | 293 | 122 | 207 |
| No. of recurrences | 198 | 139 | 46 | 90 |
| Mean age at onset of recurrence, y | 40 | 48‡ | 49 | 50§ |
| Observation period, y | 3896 | 1499 | 615 | 998 |
| Annual incidence, % (95% CI) | 5.1 (4.4-5.8) | 9.3 (7.8-10.9) | 7.5 (5.5-10.0) | 9.0 (7.3-11.1) |
| Relative risk (95% CI) | Reference | 1.7 (1.4-2.1) | Reference | 1.2 (0.8-1.7) |
| Relative risk adjusted for | ||||
| Antithrombin deficiency | Reference | 1.7 (1.3-2.1) | Reference | 1.2 (0.8-1.8) |
| Protein C deficiency | Reference | 1.7 (1.3-2.1) | Reference | 1.4 (0.9-2.1) |
| Protein S deficiency | Reference | 1.6 (1.3-2.1) | Reference | 1.3 (0.8-2.0) |
| FV Leiden | Reference | 1.7 (1.3-2.1) | Reference | 1.2 (0.8-1.7) |
| FVIII more than 150 IU/dL | Reference | 1.6 (1.3-2.0) | Reference | 1.2 (0.8-1.7) |
| Prothrombin 20210G>A | Reference | 1.6 (1.3-2.0) | Reference | 1.2 (0.8-1.7) |