Regression analysis of Bmgr5 allele and bone marrow engraftment
| Engraftment phenotype* . | BC mice, n . | BC mice engrafting, n . | Bmgr5 allele (rs3667072 genotype) . | Odds ratio (95% CI) . | P . |
|---|---|---|---|---|---|
| Donor T-cell > 0%† | 113 | 9 | B10/B10 | 1 | |
| 87 | 28 | B10/BALB | 5.5 (2.4-12.4) | < .001 | |
| Donor T-cell > 50%‡ | 113 | 3 | B10/B10 | 1 | |
| 87 | 27 | B10/BALB | 16.5 (4.8-56.6) | < .001 |
| Engraftment phenotype* . | BC mice, n . | BC mice engrafting, n . | Bmgr5 allele (rs3667072 genotype) . | Odds ratio (95% CI) . | P . |
|---|---|---|---|---|---|
| Donor T-cell > 0%† | 113 | 9 | B10/B10 | 1 | |
| 87 | 28 | B10/BALB | 5.5 (2.4-12.4) | < .001 | |
| Donor T-cell > 50%‡ | 113 | 3 | B10/B10 | 1 | |
| 87 | 27 | B10/BALB | 16.5 (4.8-56.6) | < .001 |
BC indicates backcrossed; CI, confidence interval; B10, B10.BR; and BALB, BALB.K.
At 8 weeks after transplantation.
Total number of BC mice achieving bone marrow engraftment with donor T-cell chimerism > 0% (n = 37).
Total number of BC mice achieving bone marrow engraftment with donor T-cell chimerism > 50% (n = 30).