Multivariate survival analysis using MSI2 percentage positivity for total cellular or nuclear staining grouped categorically as either ≥ or < 75th centile for strong/3+ staining
| Covariate . | Coefficient . | SE . | P . | Exp(b) . | 95% CI of Exp(b) . |
|---|---|---|---|---|---|
| Total cellular | |||||
| Age | 0.01722 | 0.009639 | .074 | 1.0174 | 0.9984-1.0367 |
| FAB subtype | −0.04048 | 0.1002 | .6862 | 0.9603 | 0.7899-1.1676 |
| Cytogenetic subtype | 0.4073 | 0.2725 | .1349 | 1.5028 | 0.8834-2.5565 |
| WBC | 0.001446 | 0.002085 | .4879 | 1.0014 | 0.9974-1.0055 |
| MSI2 3+ ≥ or < 75th centile | 0.8409 | 0.3115 | .0069 | 2.3185 | 1.2631-4.2558 |
| Nuclear | |||||
| Age | 0.0209 | 0.01067 | .0502 | 1.0211 | 1.0001-1.0426 |
| FAB subtype | −0.03314 | 0.1024 | .7462 | 0.9674 | 0.7923-1.1812 |
| Cytogenetic subtype | 0.0572 | 0.2762 | .8359 | 1.0589 | 0.6180-1.8143 |
| WBC | 0.001128 | 0.001997 | .5723 | 1.0011 | 0.9972-1.0050 |
| MSI2 3+ ≥ or < 75th centile | 1.294 | 0.3442 | .0002 | 3.6472 | 1.8639-7.1367 |
| Covariate . | Coefficient . | SE . | P . | Exp(b) . | 95% CI of Exp(b) . |
|---|---|---|---|---|---|
| Total cellular | |||||
| Age | 0.01722 | 0.009639 | .074 | 1.0174 | 0.9984-1.0367 |
| FAB subtype | −0.04048 | 0.1002 | .6862 | 0.9603 | 0.7899-1.1676 |
| Cytogenetic subtype | 0.4073 | 0.2725 | .1349 | 1.5028 | 0.8834-2.5565 |
| WBC | 0.001446 | 0.002085 | .4879 | 1.0014 | 0.9974-1.0055 |
| MSI2 3+ ≥ or < 75th centile | 0.8409 | 0.3115 | .0069 | 2.3185 | 1.2631-4.2558 |
| Nuclear | |||||
| Age | 0.0209 | 0.01067 | .0502 | 1.0211 | 1.0001-1.0426 |
| FAB subtype | −0.03314 | 0.1024 | .7462 | 0.9674 | 0.7923-1.1812 |
| Cytogenetic subtype | 0.0572 | 0.2762 | .8359 | 1.0589 | 0.6180-1.8143 |
| WBC | 0.001128 | 0.001997 | .5723 | 1.0011 | 0.9972-1.0050 |
| MSI2 3+ ≥ or < 75th centile | 1.294 | 0.3442 | .0002 | 3.6472 | 1.8639-7.1367 |
Covariates used: age at diagnosis, FAB subtype, cytogenetic subtype, and WBC at diagnosis.