Bone marrow progenitors
| . | WT . | KO . | ||||
|---|---|---|---|---|---|---|
| Mouse 1 . | Mouse 2 . | Mouse 3 . | Mouse 1 . | Mouse 2 . | Mouse 3 . | |
| BFU-E | 25 | 7 | 28 | 0 | 0 | 0 |
| CFU-GM | 42 | 17 | 31 | 0 | 0 | 0 |
| CFU-GEMM | 4 | 1 | 6 | 0 | 0 | 0 |
| Total | 71 | 25 | 65 | 0 | 0 | 0 |
| . | WT . | KO . | ||||
|---|---|---|---|---|---|---|
| Mouse 1 . | Mouse 2 . | Mouse 3 . | Mouse 1 . | Mouse 2 . | Mouse 3 . | |
| BFU-E | 25 | 7 | 28 | 0 | 0 | 0 |
| CFU-GM | 42 | 17 | 31 | 0 | 0 | 0 |
| CFU-GEMM | 4 | 1 | 6 | 0 | 0 | 0 |
| Total | 71 | 25 | 65 | 0 | 0 | 0 |
A total of 40 000 bone marrow nucleated cells from postnatal day 12 and 13 mice (3 WT and 3 KO) were plated in duplicate in methylcellulose medium and the number of colonies determined 12 days after plating.