Table 1 Serum and urine analyses for... | American Society of Hematology

Table 1

Serum and urine analyses for renal function (n = 12 per group)

	Wild-type controls	Ctns^−/− controls	WT BMCs	Ctns^−/− BMCs	WT MSCs
Serum
Creatinine, mg/dL	0.34 ± 0.06	0.49 ± 0.30*†	0.35 ± 0.07	0.43 ± 0.10*†	0.38 ± 0.11
Creatinine clearance, μL/min	79.40 ± 74.24	32.28 ± 42.58	65.65 ± 72.34	43.04 ± 34.46	85.35 ± 64.60
Urea, mg/dL	36.54 ± 1.55	56.92 ± 18.41*†	23.83 ± 19.62	74.95 ± 17.32*†	41.98 ± 4.85†
Phosphate, mg/dL	18.31 ± 3.06	23.09 ± 4.70†	10.95 ± 6.82	10.57 ± 7.53	11.86 ± 6.35
Alkaline phophatase, IU/L	60.54 ± 23.57	67.35 ± 26.75	75.77 ± 21.10	67.76 ± 18.10	55.73 ± 16.20
Urine
Phosphate, μmol/24 h	3.50 ± 2.29	11.00 ± 4.90*†	3.75 ± 2.35	2.70 ± 2.87	5.11 ± 3.29
Protein, mg/24 h	10.16 ± 6.21	17.28 ± 8.45	9.37 ± 6.91	8.35 ± 4.35	11.43 ± 7.08

	Wild-type controls	Ctns^−/− controls	WT BMCs	Ctns^−/− BMCs	WT MSCs
Serum
Creatinine, mg/dL	0.34 ± 0.06	0.49 ± 0.30*†	0.35 ± 0.07	0.43 ± 0.10*†	0.38 ± 0.11
Creatinine clearance, μL/min	79.40 ± 74.24	32.28 ± 42.58	65.65 ± 72.34	43.04 ± 34.46	85.35 ± 64.60
Urea, mg/dL	36.54 ± 1.55	56.92 ± 18.41*†	23.83 ± 19.62	74.95 ± 17.32*†	41.98 ± 4.85†
Phosphate, mg/dL	18.31 ± 3.06	23.09 ± 4.70†	10.95 ± 6.82	10.57 ± 7.53	11.86 ± 6.35
Alkaline phophatase, IU/L	60.54 ± 23.57	67.35 ± 26.75	75.77 ± 21.10	67.76 ± 18.10	55.73 ± 16.20
Urine
Phosphate, μmol/24 h	3.50 ± 2.29	11.00 ± 4.90*†	3.75 ± 2.35	2.70 ± 2.87	5.11 ± 3.29
Protein, mg/24 h	10.16 ± 6.21	17.28 ± 8.45	9.37 ± 6.91	8.35 ± 4.35	11.43 ± 7.08

Wild-type controls indicate nontreated WT C57BL/6 mice; Ctns^−/− controls, nontreated C57BL/6 Ctns^−/− mice; WT BMCs, Ctns^−/− mice treated with WT BMCs; Ctns^−/− BMCs, Ctns^−/− mice treated with Ctns^−/− BMCs; and WT MSCs, Ctns^−/− mice treated with WT MSCs.

P < .05 vs wild-type mice.

†

P < .05 vs Ctns^−/− WT BMCs.

View Large

This Feature Is Available To Subscribers Only