Table 5 Cystine content in the different... | American Society of Hematology

Table 5

Cystine content in the different tissues of mice treated with Sca1⁺ HSC compared with wild-type and Ctns^−/− controls

Cystine content, nmol half-cystine/mg protein	Wild-type mice	Ctns^−/− mice	Ctns^−/− mice Sca1⁺ HSC	Percentage cystine decrease in Sca1-transplanted vs Ctns^−/− mice
Brain	0.02 ± 0.01	1.33 ± 0.40	0.57 ± 0.13*	57.5
Eye	0.04 ± 0.01	47.46 ± 14.95	9.25 ± 1.33*	80.5
Heart	0.14 ± 0.05	58.85 ± 14.28	5.48 ± 2.33*	90.7
Kidney	0.19 ± 0.06	112.85 ± 59.72	63.72 ± 49.40*	43.5
Liver	0.02 ± 0.01	60.21 ± 20.58	4.07 ± 1.83*	93.2
Muscle	0.22 ± 0.10	29.19 ± 9.96	6.71 ± 1.44*	77.0
Spleen	0.06 ± 0.03	168.75 ± 52.08	16.76 ± 16.69*	90.1

Cystine content, nmol half-cystine/mg protein	Wild-type mice	Ctns^−/− mice	Ctns^−/− mice Sca1⁺ HSC	Percentage cystine decrease in Sca1-transplanted vs Ctns^−/− mice
Brain	0.02 ± 0.01	1.33 ± 0.40	0.57 ± 0.13*	57.5
Eye	0.04 ± 0.01	47.46 ± 14.95	9.25 ± 1.33*	80.5
Heart	0.14 ± 0.05	58.85 ± 14.28	5.48 ± 2.33*	90.7
Kidney	0.19 ± 0.06	112.85 ± 59.72	63.72 ± 49.40*	43.5
Liver	0.02 ± 0.01	60.21 ± 20.58	4.07 ± 1.83*	93.2
Muscle	0.22 ± 0.10	29.19 ± 9.96	6.71 ± 1.44*	77.0
Spleen	0.06 ± 0.03	168.75 ± 52.08	16.76 ± 16.69*	90.1

P < .05 vs Ctns^−/− control mice.