Table 1 Blockade of endothelial NF-κB... | American Society of Hematology

Table 1

Blockade of endothelial NF-κB signaling restored plasma levels of TPC and APC

	WT-Con	TG-Con	WT-LPS	TG-LPS
TPC, mOD units	73.4 ± 2.4	72.0 ± 3.2	26.0 ± 6.2*	58.5 ± 4.7†
APC, mOD units	45.6 ± 1.6	43.0 ± 1.3	2.8 ± 1.9*	29.9 ± 4.1†

	WT-Con	TG-Con	WT-LPS	TG-LPS
TPC, mOD units	73.4 ± 2.4	72.0 ± 3.2	26.0 ± 6.2*	58.5 ± 4.7†
APC, mOD units	45.6 ± 1.6	43.0 ± 1.3	2.8 ± 1.9*	29.9 ± 4.1†

Plasma was collected at 6 hours after LPS. Plasma levels of total (TPC) and activated protein C (APC) were determined by enzyme capture assay. Data are mean ± SEM of 7 mice.

mOD indicates milli-optical density.

P < .02 compared with any other group.

†

P < .02 compared with WT-LPS group.

View Large

This Feature Is Available To Subscribers Only