Univariate analysis of common prognostic markers and response to PCLI as predictors of overall survival
| Prognostic variable . | Proportional hazard ratio . | 95% CI . | P . |
|---|---|---|---|
| Age > 65 y | 1.15 | 0.73-1.67 | .60 |
| Albumin < 3.5 g/dL | 1.23 | 0.84-1.78 | .28 |
| β2M > 3.5 mg/dL | 1.47 | 1.01-2.14 | .042* |
| Creatinine > 1.4 | 1.51 | 1.02-2.22 | .042* |
| Hemoglobin < 10 g/dL | 1.20 | 0.82-1.74 | .34 |
| Serum M-spike response < 50% | 1.64 | 1.13-2.38 | .009* |
| PCLI response < 60% | 1.56 | 1.08-2.25 | .019* |
| Initial PCLI | |||
| ≥ 3% | 2.54 | 1.50-4.08 | < .001* |
| ≥ 1% | 1.42 | 0.96-2.12 | .08 |
| Prognostic variable . | Proportional hazard ratio . | 95% CI . | P . |
|---|---|---|---|
| Age > 65 y | 1.15 | 0.73-1.67 | .60 |
| Albumin < 3.5 g/dL | 1.23 | 0.84-1.78 | .28 |
| β2M > 3.5 mg/dL | 1.47 | 1.01-2.14 | .042* |
| Creatinine > 1.4 | 1.51 | 1.02-2.22 | .042* |
| Hemoglobin < 10 g/dL | 1.20 | 0.82-1.74 | .34 |
| Serum M-spike response < 50% | 1.64 | 1.13-2.38 | .009* |
| PCLI response < 60% | 1.56 | 1.08-2.25 | .019* |
| Initial PCLI | |||
| ≥ 3% | 2.54 | 1.50-4.08 | < .001* |
| ≥ 1% | 1.42 | 0.96-2.12 | .08 |
β2M indicates β2-microglobulin; CI, confidence interval; and PCLI, plasma cell labeling index.
Statistically significant.