KEGG pathways with the most genes up-regulated in G-CSF–mobilized CD34+ cells and plerixafor-mobilized CD34+ cells
| Pathways with genes up-regulated by G-CSF . | Pathways with genes up-regulated by plerixafor . | ||
|---|---|---|---|
| Pathway . | No. of genes in pathway . | Pathway . | No. of genes in pathway . |
| Cytokine-cytokine receptor interaction | 30 | Cytokine-cytokine receptor interaction | 29 |
| Jak-STAT signaling pathway | 25 | Calcium signaling pathway | 27 |
| MAPK signaling pathway | 24 | T-cell receptor signaling pathway | 27 |
| Focal adhesion | 22 | Hematopoietic cell lineage | 24 |
| Insulin signaling pathway | 21 | Wnt signaling pathway | 22 |
| Hematopoietic cell lineage | 20 | Primary immunodeficiency | 21 |
| Natural killer cell–mediated cytotoxicity | 19 | Cell cycle | 20 |
| Purine metabolism | 19 | MAPK signaling pathway | 20 |
| ErbB signaling pathway | 16 | Focal adhesion | 19 |
| VEGF signaling pathway | 15 | Natural killer cell mediated cytotoxicity | 19 |
| Regulation of actin cytoskeleton | 14 | TGF-beta signaling pathway | 19 |
| Toll-like receptor signaling pathway | 14 | Fc epsilon RI signaling pathway | 18 |
| Tyrosine metabolism | 14 | Jak-STAT signaling pathway | 18 |
| Acute myeloid leukemia | 13 | GnRH signaling pathway | 15 |
| Fc epsilon RI signaling pathway | 13 | Cell adhesion molecules | 14 |
| GnRH signaling pathway | 13 | Tight junction | 13 |
| Neuroactive ligand-receptor interaction | 13 | Adherens junction | 12 |
| Wnt signaling pathway | 13 | Antigen processing and presentation | 12 |
| Calcium signaling pathway | 12 | B-cell receptor signaling pathway | 12 |
| Complement and coagulation cascades | 12 | Neuroactive ligand-receptor interaction | 12 |
| Fructose and mannose metabolism | 12 | Gap junction | 11 |
| Glycine, serine, and threonine metabolism | 12 | Long-term depression | 11 |
| Leukocyte transendothelial migration | 12 | Melanogenesis | 11 |
| Melanogenesis | 12 | Regulation of actin cytoskeleton | 11 |
| Pathways with genes up-regulated by G-CSF . | Pathways with genes up-regulated by plerixafor . | ||
|---|---|---|---|
| Pathway . | No. of genes in pathway . | Pathway . | No. of genes in pathway . |
| Cytokine-cytokine receptor interaction | 30 | Cytokine-cytokine receptor interaction | 29 |
| Jak-STAT signaling pathway | 25 | Calcium signaling pathway | 27 |
| MAPK signaling pathway | 24 | T-cell receptor signaling pathway | 27 |
| Focal adhesion | 22 | Hematopoietic cell lineage | 24 |
| Insulin signaling pathway | 21 | Wnt signaling pathway | 22 |
| Hematopoietic cell lineage | 20 | Primary immunodeficiency | 21 |
| Natural killer cell–mediated cytotoxicity | 19 | Cell cycle | 20 |
| Purine metabolism | 19 | MAPK signaling pathway | 20 |
| ErbB signaling pathway | 16 | Focal adhesion | 19 |
| VEGF signaling pathway | 15 | Natural killer cell mediated cytotoxicity | 19 |
| Regulation of actin cytoskeleton | 14 | TGF-beta signaling pathway | 19 |
| Toll-like receptor signaling pathway | 14 | Fc epsilon RI signaling pathway | 18 |
| Tyrosine metabolism | 14 | Jak-STAT signaling pathway | 18 |
| Acute myeloid leukemia | 13 | GnRH signaling pathway | 15 |
| Fc epsilon RI signaling pathway | 13 | Cell adhesion molecules | 14 |
| GnRH signaling pathway | 13 | Tight junction | 13 |
| Neuroactive ligand-receptor interaction | 13 | Adherens junction | 12 |
| Wnt signaling pathway | 13 | Antigen processing and presentation | 12 |
| Calcium signaling pathway | 12 | B-cell receptor signaling pathway | 12 |
| Complement and coagulation cascades | 12 | Neuroactive ligand-receptor interaction | 12 |
| Fructose and mannose metabolism | 12 | Gap junction | 11 |
| Glycine, serine, and threonine metabolism | 12 | Long-term depression | 11 |
| Leukocyte transendothelial migration | 12 | Melanogenesis | 11 |
| Melanogenesis | 12 | Regulation of actin cytoskeleton | 11 |