Table 3

Risk of assisted reproductive technology failure with individual anti-phospholipid antibodies

AntibodyNo. of studies (no. of patients)OR (95% CI)I2, % (P)
Lupus anticoagulant 12 (2013) 5.60 (2.16-14.55) 0 (.80) 
Anti-cardiolipin 15 (2685) 3.27 (0.92-11.63) 76 (< .001) 
Anti-phosphatidylserine 3 (820) 4.51 (1.37-14.80) 0 (.46) 
Anti-phosphatidylinositol 2 (408) 5.03 (1.13-22.47) 0 (.82) 
Anti-phosphatidic acid 1 (394) 4.65 (1.10-19.74) — 
Anti-phosphatidylglycerol 1 (394) 2.77 (1.06-7.20) — 
Anti–β2-glycoprotein I 3 (574) 1.19 (0.39-3.67) — 
Antiphosphatidylethanolamine 2 (408) 1.31 (0.46-3.71) 70 (.27) 
AntibodyNo. of studies (no. of patients)OR (95% CI)I2, % (P)
Lupus anticoagulant 12 (2013) 5.60 (2.16-14.55) 0 (.80) 
Anti-cardiolipin 15 (2685) 3.27 (0.92-11.63) 76 (< .001) 
Anti-phosphatidylserine 3 (820) 4.51 (1.37-14.80) 0 (.46) 
Anti-phosphatidylinositol 2 (408) 5.03 (1.13-22.47) 0 (.82) 
Anti-phosphatidic acid 1 (394) 4.65 (1.10-19.74) — 
Anti-phosphatidylglycerol 1 (394) 2.77 (1.06-7.20) — 
Anti–β2-glycoprotein I 3 (574) 1.19 (0.39-3.67) — 
Antiphosphatidylethanolamine 2 (408) 1.31 (0.46-3.71) 70 (.27) 

— indicates not applicable.

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