Table 2

Kinetic constants, obtained by SPR

Factor B binding to C3(H2O)
WTK325ND254G
Kassociation 0.18 × 105 2.91 × 105 4.69 × 105 
Kdissociation 18.7 × 10−4 5.20 × 10−4 6.40 × 10−4 
Ka 9.56 × 106 5.60 × 108 7.33 × 108 
KD 1.05 × 107 1.79 × 109 1.36 × 109 
Factor B binding to C3(H2O)
WTK325ND254G
Kassociation 0.18 × 105 2.91 × 105 4.69 × 105 
Kdissociation 18.7 × 10−4 5.20 × 10−4 6.40 × 10−4 
Ka 9.56 × 106 5.60 × 108 7.33 × 108 
KD 1.05 × 107 1.79 × 109 1.36 × 109 
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