Table 1

Patients' characteristics of miRNA screening cohort

Negative for feature, n/%Positive for feature, n/%
Thymidine kinase (> 10 U/L) 34/50 (68.0%) 16/50 (32.0%) 
CD38 (> 10% positive CLL cells) 34/50 (68.0%) 16/50 (32.0%) 
ZAP70 (> 20% positive CLL cells) 25/50 (50.0%) 25/50 (50.0%) 
IgVH hypermutational status (homology > 98%) 20/31 (64.5%) 11/31 (35.4%) 
Negative for feature, n/%Positive for feature, n/%
Thymidine kinase (> 10 U/L) 34/50 (68.0%) 16/50 (32.0%) 
CD38 (> 10% positive CLL cells) 34/50 (68.0%) 16/50 (32.0%) 
ZAP70 (> 20% positive CLL cells) 25/50 (50.0%) 25/50 (50.0%) 
IgVH hypermutational status (homology > 98%) 20/31 (64.5%) 11/31 (35.4%) 

Molecular features of 50 patients being diagnosed with CLL were assessed before miRNA profiling was performed.

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