Donor lymphoid chimerism
| . | asmase+/+ . | asmase−/− . |
|---|---|---|
| B cells | 34.4 ± 0.8 | 97.0 ± 0.1* |
| CD4+ T cells | 2.9 ± 0.6 | 20.8 ± 1.1* |
| CD8+ T cells | 1.5 ± 0.4 | 3.7 ± 0.6 |
| . | asmase+/+ . | asmase−/− . |
|---|---|---|
| B cells | 34.4 ± 0.8 | 97.0 ± 0.1* |
| CD4+ T cells | 2.9 ± 0.6 | 20.8 ± 1.1* |
| CD8+ T cells | 1.5 ± 0.4 | 3.7 ± 0.6 |
C57BL/6asmase+/+ and C57BL/6asmase−/− recipients were infused with 5 × 106 LP/J TCD-BM as described in “Mice and BMT.” Spleens were harvested 14 days thereafter, and multicolor flow cytometry was performed using fluorescent-labeled antibodies to B220 (B cells), CD4, and CD8. Data are expressed as percentage of total population of each lineage that is donor derived (Ly9.1+) ± SE.
P < .005 versus asmase+/+.