Table 3 miRNAs predictors of the... | American Society of Hematology

Table 3

miRNAs predictors of the cytogenetic subgroups in CLL

miRNA	Prediction analysis of microarray score*					Chromosome map
miRNA	11q deletion	13q deletion	17p deletion	Normal karyotype	Trisomy 12	Chromosome map
miR-370	0.19	0.55	−1.22	0.28	0.19	14q32.31
miR-16-2*	−1.04	0.11	0.24	0.16	0.20	3q26.1
miR-572	0.76	0.53	−0.99	−0.36	0.15	4p15.33
miR-130a*	−0.93	0.84	0.60	−0.03	−0.51	11q12.1
miR-590-5p	0.26	0.83	−0.80	−0.35	0.07	7q11.23
miR-151-3p	−0.40	0.31	−0.82	0.35	0.35	8q24.3
miR-640	−0.51	0.68	0.41	0.32	−0.70	19p13.11
miR-548a-3p	0.62	−0.03	−0.20	−0.26	0.00	6p22.3
miR-556-3p	0.44	−0.60	0.00	0.17	0.08	8q22.3
miR-148a	0.23	0.18	0.36	0.10	−0.57	1q23.3
miR-29b-1*	0.06	0.01	−0.57	−0.09	0.42	7p15.2
miR-585	0.17	−0.22	0.22	−0.57	0.28	7q32.3
miR-499-5p	−0.03	−0.55	0.28	0.16	0.11	5q35.1
miR-99b	0.29	0.55	0.00	−0.28	−0.36	20q11.22
miR-146a	−0.06	−0.23	−0.36	−0.14	0.54	5q33.3
miR-200c	−0.08	0.51	−0.27	−0.40	0.14	12p13.31
miR-498	0.22	−0.50	−0.06	0.13	0.20	19q13.41
miR-377	0.14	−0.43	0.10	0.13	0.08	14q32.31
miR-146b-5p	−0.12	−0.03	−0.32	−0.18	0.43	10q24.32
miR-593	−0.29	0.43	−0.08	−0.13	−0.01	7q32.1
miR-205	−0.33	0.39	0.42	−0.03	−0.38	1q32.2
miR-136	0.40	−0.24	−0.04	−0.01	0.00	14q32.31
miR-193a-5p	0.19	−0.28	−0.24	−0.17	0.37	17q11.2
miR-543	0.14	−0.37	−0.03	0.26	0.05	14q32.31
miR-29c	−0.16	0.17	−0.33	0.20	0.07	1q32.2
miR-29a*	0.31	−0.25	−0.04	0.00	0.04	7q32.3
miR-532-3p	−0.04	−0.06	0.21	0.31	−0.28	Xp11.23
miR-29b	−0.30	0.18	−0.25	0.17	0.09	7q32.3
miR-34a	0.27	−0.22	−0.23	−0.01	0.17	1p36.23
miR-202*	0.23	−0.26	0.01	−0.26	0.22	10q26.3
miR-142-5p	−0.22	0.24	0.13	0.02	−0.16	17q22
miR-155	0.21	−0.10	0.18	0.08	−0.22	21q21.3

miRNA	Prediction analysis of microarray score*					Chromosome map
miRNA	11q deletion	13q deletion	17p deletion	Normal karyotype	Trisomy 12	Chromosome map
miR-370	0.19	0.55	−1.22	0.28	0.19	14q32.31
miR-16-2*	−1.04	0.11	0.24	0.16	0.20	3q26.1
miR-572	0.76	0.53	−0.99	−0.36	0.15	4p15.33
miR-130a*	−0.93	0.84	0.60	−0.03	−0.51	11q12.1
miR-590-5p	0.26	0.83	−0.80	−0.35	0.07	7q11.23
miR-151-3p	−0.40	0.31	−0.82	0.35	0.35	8q24.3
miR-640	−0.51	0.68	0.41	0.32	−0.70	19p13.11
miR-548a-3p	0.62	−0.03	−0.20	−0.26	0.00	6p22.3
miR-556-3p	0.44	−0.60	0.00	0.17	0.08	8q22.3
miR-148a	0.23	0.18	0.36	0.10	−0.57	1q23.3
miR-29b-1*	0.06	0.01	−0.57	−0.09	0.42	7p15.2
miR-585	0.17	−0.22	0.22	−0.57	0.28	7q32.3
miR-499-5p	−0.03	−0.55	0.28	0.16	0.11	5q35.1
miR-99b	0.29	0.55	0.00	−0.28	−0.36	20q11.22
miR-146a	−0.06	−0.23	−0.36	−0.14	0.54	5q33.3
miR-200c	−0.08	0.51	−0.27	−0.40	0.14	12p13.31
miR-498	0.22	−0.50	−0.06	0.13	0.20	19q13.41
miR-377	0.14	−0.43	0.10	0.13	0.08	14q32.31
miR-146b-5p	−0.12	−0.03	−0.32	−0.18	0.43	10q24.32
miR-593	−0.29	0.43	−0.08	−0.13	−0.01	7q32.1
miR-205	−0.33	0.39	0.42	−0.03	−0.38	1q32.2
miR-136	0.40	−0.24	−0.04	−0.01	0.00	14q32.31
miR-193a-5p	0.19	−0.28	−0.24	−0.17	0.37	17q11.2
miR-543	0.14	−0.37	−0.03	0.26	0.05	14q32.31
miR-29c	−0.16	0.17	−0.33	0.20	0.07	1q32.2
miR-29a*	0.31	−0.25	−0.04	0.00	0.04	7q32.3
miR-532-3p	−0.04	−0.06	0.21	0.31	−0.28	Xp11.23
miR-29b	−0.30	0.18	−0.25	0.17	0.09	7q32.3
miR-34a	0.27	−0.22	−0.23	−0.01	0.17	1p36.23
miR-202*	0.23	−0.26	0.01	−0.26	0.22	10q26.3
miR-142-5p	−0.22	0.24	0.13	0.02	−0.16	17q22
miR-155	0.21	−0.10	0.18	0.08	−0.22	21q21.3

CLL indicates chronic lymphocytic leukemia; and miRNA, microRNA.

Log ratio of expression relative to the shrunken centroids.