Adoptive transfer of 106 NKT cells into NY1DD × Rag1−/− increases absolute numbers of pulmonary PMNs and NK cells
| Cells, 105 . | (a) NY1DD (n = 8) . | (b) NY1DD × Rag1−/− (n = 8) . | (c) NY1DD × Rag1−/− + NKT cells (n = 4) . |
|---|---|---|---|
| PMNs | 2.34 (0.4) | 1.63 (0.46) | 6.64 (1.9)† |
| NK | 4.3 (0.85) | 6.71 (1.28)* | 12.32 (1.03)† |
| Cells, 105 . | (a) NY1DD (n = 8) . | (b) NY1DD × Rag1−/− (n = 8) . | (c) NY1DD × Rag1−/− + NKT cells (n = 4) . |
|---|---|---|---|
| PMNs | 2.34 (0.4) | 1.63 (0.46) | 6.64 (1.9)† |
| NK | 4.3 (0.85) | 6.71 (1.28)* | 12.32 (1.03)† |
At baseline, NY1DD × Rag1−/− have significantly increased pulmonary NK cells. Lungs were harvested 4 days after adoptive transfer of NKT cells harvested from spleen (see “Methods”). Data represent mean (SEM). Data were analyzed by one-way ANOVA with Neuman-Keuls posttesting. A P value less than .05 was considered significant.
Column b versus column a.
Column c versus columns b and a.