Neutralization of CXCR3 in NY1DD mice decreases pulmonary leukocyte infiltration
| Cells, right lung (105) . | NY1DD serum (n = 8) . | NY1DD anti-CXCR3 (n = 8) . | P . |
|---|---|---|---|
| PMNs | 1.12 (0.35) | 0.34 (0.07) | .037 |
| CD4 | 1.94 (0.29) | 0.54 (0.05) | .001 |
| CD8 | 1.24 (0.15) | 0.64 (0.14) | .01 |
| NK | 3.85 (0.45) | 1.70 (0.25) | .002 |
| NKT | 0.37 (0.07) | 0.14 (0.03) | .045 |
| Cells, right lung (105) . | NY1DD serum (n = 8) . | NY1DD anti-CXCR3 (n = 8) . | P . |
|---|---|---|---|
| PMNs | 1.12 (0.35) | 0.34 (0.07) | .037 |
| CD4 | 1.94 (0.29) | 0.54 (0.05) | .001 |
| CD8 | 1.24 (0.15) | 0.64 (0.14) | .01 |
| NK | 3.85 (0.45) | 1.70 (0.25) | .002 |
| NKT | 0.37 (0.07) | 0.14 (0.03) | .045 |
Mice were injected (1 mL/day for 7 days) subcutaneously with either goat serum or goat anti-CXCR3 (see “Methods”). Total cells in the right lung lobes were counted. Data represent mean (SEM). P values were calculated by an unpaired t test.