Table 3 Expression of loci containing... | American Society of Hematology

Table 3

Expression of loci containing one or more confirmed STAT6 binding motifs in PMBL cases

Gene	Microarray ID	No STAT6 mutation (n = 5)*	STAT6 mutation (n = 7)*	Fold change†	P‡
FCER2	35220	−1.26	−0.24	2.02	.26
FCER2	17521	−1.37	−0.36	2.01	.37
IL4	25233	−0.37	0.03	1.32	.32
IL4	34968	−0.46	−0.08	1.30	.40
IL4R	28597	1.05	1.41	1.28	.15
IL4R	19256	1.69	2.09	1.32	.25
CCL17	29233	−1.26	−0.82	1.36	.60
CD40	27399	0.11	0.53	1.34	.07
CD40	16913	0.10	0.45	1.28	.12
BCL2L1	16454	0.02	−0.15	0.89	.30
BCL2L1	24267	0.10	−0.03	0.92	.53
IL4I1	149016	2.25	2.40	1.11	.75
IL4I1	149017	1.57	1.94	1.29	.23

Gene	Microarray ID	No STAT6 mutation (n = 5)*	STAT6 mutation (n = 7)*	Fold change†	P‡
FCER2	35220	−1.26	−0.24	2.02	.26
FCER2	17521	−1.37	−0.36	2.01	.37
IL4	25233	−0.37	0.03	1.32	.32
IL4	34968	−0.46	−0.08	1.30	.40
IL4R	28597	1.05	1.41	1.28	.15
IL4R	19256	1.69	2.09	1.32	.25
CCL17	29233	−1.26	−0.82	1.36	.60
CD40	27399	0.11	0.53	1.34	.07
CD40	16913	0.10	0.45	1.28	.12
BCL2L1	16454	0.02	−0.15	0.89	.30
BCL2L1	24267	0.10	−0.03	0.92	.53
IL4I1	149016	2.25	2.40	1.11	.75
IL4I1	149017	1.57	1.94	1.29	.23

Mean expression levels (log2) in cases with (n = 7) or without (n = 5) STAT6 mutation from Rosenwald et al.¹⁹

Fold change, ratio of mean expression in mutated cases relative to WT cases.

P values (by Student t test) were not corrected for multiple comparisons.