Table 1 Genetic tests to be performed in... | American Society of Hematology

Table 1

Genetic tests to be performed in myeloma patients at diagnosis

Essential tests for all patients	Desirable tests	Investigational tests for trials
Plasma cell–specific FISH analysis t(4;14) (p16;q32) t(14;16) (q32;q23) 17p13	Cytogenetics Plasma cell–specific FISH analysis Hyperdiploidy t(11;14)(q13;q32) 1q amplifications 1 p deletions Loss of 12p Gains of Cr5	Gene expression profiling aCGH/SNP arrays

Essential tests for all patients	Desirable tests	Investigational tests for trials
Plasma cell–specific FISH analysis t(4;14) (p16;q32) t(14;16) (q32;q23) 17p13	Cytogenetics Plasma cell–specific FISH analysis Hyperdiploidy t(11;14)(q13;q32) 1q amplifications 1 p deletions Loss of 12p Gains of Cr5	Gene expression profiling aCGH/SNP arrays

FISH indicates fluorescent in situ hybridizaton; and aCGH/SNP, array comparative genomic hybridization/single nucleotide polymorphisms.