Table 4

Sites of thrombosis according to leukocytosis at diagnosis in 657 patients with ET8

7.1-10 × 109/L white blood cells*
More than 10 × 109/L white blood cells*
HR (95% CI)PHR (95% CI)P
Major thrombosis 2.21 (1.05-4.65) .036 3.27 (1.54-6.95) .002 
Arterial thrombosis 2.07 (0.83-5.20) .121 3.12 (1.20-8.08) .019 
Myocardial infarction (IMA) 5.82 (0.64-53.2) .118 8.08 (1.00-65.5) .050 
Stroke/TIA 0.88 (0.29-2.67) .824 1.32 (0.42-4.11) .631 
Venous thrombosis 1.40 (0.49-4.04) .534 2.51 (0.86-7.29) .092 
7.1-10 × 109/L white blood cells*
More than 10 × 109/L white blood cells*
HR (95% CI)PHR (95% CI)P
Major thrombosis 2.21 (1.05-4.65) .036 3.27 (1.54-6.95) .002 
Arterial thrombosis 2.07 (0.83-5.20) .121 3.12 (1.20-8.08) .019 
Myocardial infarction (IMA) 5.82 (0.64-53.2) .118 8.08 (1.00-65.5) .050 
Stroke/TIA 0.88 (0.29-2.67) .824 1.32 (0.42-4.11) .631 
Venous thrombosis 1.40 (0.49-4.04) .534 2.51 (0.86-7.29) .092 

Multivariable models adjusted for information collected at diagnosis, including center, sex, standard risk factors, hemoglobin, hematocrit, and platelet count.

*

Reference category: WBC count 7 × 109/L or lower.

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