Clinical response within subgroups for the intent-to-treat population
| . | Response, no. (%) . | |
|---|---|---|
| CR + PR . | CR + PR + MR . | |
| Total group, N = 222 | 58 (26) | 98 (44) |
| Age | ||
| 65 y or younger, n = 125 | 30 (24) | 52 (42) |
| Older than 65 y, n = 97 | 28 (29) | 46 (47) |
| Sex | ||
| Male, n = 123 | 36 (29) | 55 (45) |
| Female, n = 99 | 22 (22) | 43 (43) |
| ECOG performance status* | ||
| 0, n = 71 | 18 (25) | 26 (37) |
| 1, n = 112 | 30 (27) | 52 (46) |
| 2, n = 26 | 7 (27) | 14 (54) |
| No. of prior SCTs | ||
| 0, n = 122 | 32 (26) | 57 (47) |
| 1, n = 9 | 2 (22) | 3 (33) |
| 2 or more, n = 91 | 24 (26) | 38 (42) |
| No. of prior anti–multiple myeloma treatment regimens | ||
| 1, n = 18 | 3 (17) | 6 (33) |
| 2, n = 55 | 16 (29) | 27 (49) |
| 3, n = 47 | 11 (23) | 18 (38) |
| More than 3, n = 102 | 28 (27) | 47 (46) |
| Prior radiotherapy | ||
| Yes, n = 96 | 28 (29) | 42 (44) |
| No, n = 126 | 30 (24) | 56 (44) |
| Median duration of treatment, d | 400.5 | 266.0 |
| . | Response, no. (%) . | |
|---|---|---|
| CR + PR . | CR + PR + MR . | |
| Total group, N = 222 | 58 (26) | 98 (44) |
| Age | ||
| 65 y or younger, n = 125 | 30 (24) | 52 (42) |
| Older than 65 y, n = 97 | 28 (29) | 46 (47) |
| Sex | ||
| Male, n = 123 | 36 (29) | 55 (45) |
| Female, n = 99 | 22 (22) | 43 (43) |
| ECOG performance status* | ||
| 0, n = 71 | 18 (25) | 26 (37) |
| 1, n = 112 | 30 (27) | 52 (46) |
| 2, n = 26 | 7 (27) | 14 (54) |
| No. of prior SCTs | ||
| 0, n = 122 | 32 (26) | 57 (47) |
| 1, n = 9 | 2 (22) | 3 (33) |
| 2 or more, n = 91 | 24 (26) | 38 (42) |
| No. of prior anti–multiple myeloma treatment regimens | ||
| 1, n = 18 | 3 (17) | 6 (33) |
| 2, n = 55 | 16 (29) | 27 (49) |
| 3, n = 47 | 11 (23) | 18 (38) |
| More than 3, n = 102 | 28 (27) | 47 (46) |
| Prior radiotherapy | ||
| Yes, n = 96 | 28 (29) | 42 (44) |
| No, n = 126 | 30 (24) | 56 (44) |
| Median duration of treatment, d | 400.5 | 266.0 |
CR indicates complete response; ECOG, Eastern Cooperative Oncology Group; MR, minimal response; PR, partial response; and SCT, stem cell transplantation.
Total number of patients does not equal 222 due to 13 patients having missing ECOG data.