Genes expressed either differentially or not between resident and inflammatory monocytes
. | Up-regulated . | . | Down-regulated . | ||||
---|---|---|---|---|---|---|---|
Fold more . | ΔCt . | P . | Fold less . | ΔCt . | P . | ||
Arg1 | 58.7 | 11.5 | < .001 | Chi3l3/Ym1 | −18.0 | 6.4 | < .001 |
Cxcl12 | 20.5 | 15.1 | < .001 | Sell | −9.5 | 8.1 | < .001 |
Lyve1 | 14.7 | 12.8 | < .001 | Ccr2 | −5.6 | 7.6 | < .001 |
Stab1 | 14.1 | 16.7 | < .001 | Ptgs2 | −4.5 | 18.1 | < .001 |
Igf1 | 13.6 | 15.3 | < .001 | Not differentially expressed | |||
Cd163 | 5.2 | 13.3 | < .001 | Angpt1 | Cx3cr1 | Itga4 | Tbx21 |
Edg1 | 4.7 | 9.0 | < .001 | Angpt2 | Egf | Il4 | Tgfb1 |
Il10 | 4.4 | 16.0 | < .001 | Ccr7 | Fgf2 | Vegfr2 | Tlr4 |
Mmp9 | 3.1 | 12.3 | < .05 | Csf1R | Vegfr1 | Mmp12 | Tnf |
Mrc1 | 2.7 | 9.9 | < .05 | Cd80 | Ifng | Nos2 | Tnfrsf18 |
Il12a | 2.6 | 14.0 | < .05 | Cd86 | Il1b | Nrp1 | |
Mmp2 | 2.5 | 17.6 | < .05 |
. | Up-regulated . | . | Down-regulated . | ||||
---|---|---|---|---|---|---|---|
Fold more . | ΔCt . | P . | Fold less . | ΔCt . | P . | ||
Arg1 | 58.7 | 11.5 | < .001 | Chi3l3/Ym1 | −18.0 | 6.4 | < .001 |
Cxcl12 | 20.5 | 15.1 | < .001 | Sell | −9.5 | 8.1 | < .001 |
Lyve1 | 14.7 | 12.8 | < .001 | Ccr2 | −5.6 | 7.6 | < .001 |
Stab1 | 14.1 | 16.7 | < .001 | Ptgs2 | −4.5 | 18.1 | < .001 |
Igf1 | 13.6 | 15.3 | < .001 | Not differentially expressed | |||
Cd163 | 5.2 | 13.3 | < .001 | Angpt1 | Cx3cr1 | Itga4 | Tbx21 |
Edg1 | 4.7 | 9.0 | < .001 | Angpt2 | Egf | Il4 | Tgfb1 |
Il10 | 4.4 | 16.0 | < .001 | Ccr7 | Fgf2 | Vegfr2 | Tlr4 |
Mmp9 | 3.1 | 12.3 | < .05 | Csf1R | Vegfr1 | Mmp12 | Tnf |
Mrc1 | 2.7 | 9.9 | < .05 | Cd80 | Ifng | Nos2 | Tnfrsf18 |
Il12a | 2.6 | 14.0 | < .05 | Cd86 | Il1b | Nrp1 | |
Mmp2 | 2.5 | 17.6 | < .05 |
Bold text indicates concordant expression in resident versus inflammatory monocytes and TEMs versus TAMs. Text without bold or underlining indicates significantly up-regulated/down-regulated either in resident versus inflammatory monocytes or TEMs versus TAMs. Underlined text indicates discordant expression in resident versus inflammatory monocytes and TEMs versus TAMs.