Genes expressed either differentially or not between Tie2-GFP+ and Tie2-GFP−, Cd11b+ embryonic/fetal macrophages
| . | Up-regulated . | . | Down-regulated . | ||||
|---|---|---|---|---|---|---|---|
| Fold more . | ΔCt . | P . | Fold less . | ΔCt . | P . | ||
| Mmp12 | 39.3 | 2.3 | < .001 | Sell | −35.1 | 8.8 | < .001 |
| Igf1 | 25.0 | 7.4 | < .001 | Chi3l3/Ym1 | −15.2 | 6.1 | < .001 |
| Lyve1 | 21.0 | 3.7 | < .001 | Mmp9 | −8.3 | 6.6 | < .001 |
| Arg1 | 11.6 | 4.9 | < .001 | Egf | −7.3 | 12.3 | < .01 |
| Mrc1 | 7.2 | 2.6 | < .01 | Angpt1 | −4.4 | 11.5 | < .05 |
| Cd163 | 6.4 | 7.0 | < .01 | Not differentially expressed | |||
| Stab1 | 3.7 | 1.0 | < .05 | Angpt2 | Edg1 | Il12a | Nrp1 |
| Cx3cr1 | 3.5 | 1.0 | < .05 | Csf1r | Fgf2 | Vegfr2 | Tfrc |
| Cxcl12 | Vegfr1 | Mmp2 | Tlr4 | ||||
| . | Up-regulated . | . | Down-regulated . | ||||
|---|---|---|---|---|---|---|---|
| Fold more . | ΔCt . | P . | Fold less . | ΔCt . | P . | ||
| Mmp12 | 39.3 | 2.3 | < .001 | Sell | −35.1 | 8.8 | < .001 |
| Igf1 | 25.0 | 7.4 | < .001 | Chi3l3/Ym1 | −15.2 | 6.1 | < .001 |
| Lyve1 | 21.0 | 3.7 | < .001 | Mmp9 | −8.3 | 6.6 | < .001 |
| Arg1 | 11.6 | 4.9 | < .001 | Egf | −7.3 | 12.3 | < .01 |
| Mrc1 | 7.2 | 2.6 | < .01 | Angpt1 | −4.4 | 11.5 | < .05 |
| Cd163 | 6.4 | 7.0 | < .01 | Not differentially expressed | |||
| Stab1 | 3.7 | 1.0 | < .05 | Angpt2 | Edg1 | Il12a | Nrp1 |
| Cx3cr1 | 3.5 | 1.0 | < .05 | Csf1r | Fgf2 | Vegfr2 | Tfrc |
| Cxcl12 | Vegfr1 | Mmp2 | Tlr4 | ||||
Bold text indicates concordant expression in embryo TEMs versus embryonic macrophages and tumor TEMs versus TAMs. Text without bold or underlining indicates significantly up-regulated/down-regulated either in embryo TEMs versus embryonic macrophages or tumor TEMs versus TAMs. Underlined text indicates discordant expression in embryo TEMs versus embryonic macrophages and tumor TEMs versus TAMs.