Table 3 In vivo engraftment of... | American Society of Hematology

Table 3

In vivo engraftment of SB100X-transfected CD34⁺ HPCs

CD34 cells/mouse ID	BM		Spleen
CD34 cells/mouse ID	hCD45⁺, %	DsRed⁺hCD45⁺, %	hCD45⁺, %	DsRed⁺hCD45⁺, %
Mock
1	45.92	0.58	83.62	1.64
2	18.71	0.05	14.25	0.10
3	60.41	0.25	81.49	5.81
Median	45.92	0.25	81.49	1.64
Transposon alone
4	63.73	0.60	48.00	0.36
5	27.17	0.34	47.24	3.22
6	42.87	0.00	48.01	0.15
7	55.02	0.63	39.41	0.66
Median	48.95	0.47	47.60	0.51
Transposon + SB100X
8	64.61	1.32	70.81	2.59
9	23.29	2.92	23.69	13.43
10	8.68	1.61	33.08	0.49
11	45.95	7.32	26.85	7.11
12	29.39	7.62	18.94	5.89
13	22.74	4.02	47.99	3.32
14	70.73	27.14	69.99	18.11
15	76.82	1.56	25.39	7.37
16	47.42	8.25	52.95	6.22
17	39.42	2.65	57.30	3.99
18	16.37	28.96	18.07	34.50
19	68.73	0.57	43.29	4.28
20	78.67	0.69	69.83	5.29
21	55.57	1.06	72.16	2.12
Median	46.69	2.79	45.64	5.59

CD34 cells/mouse ID	BM		Spleen
CD34 cells/mouse ID	hCD45⁺, %	DsRed⁺hCD45⁺, %	hCD45⁺, %	DsRed⁺hCD45⁺, %
Mock
1	45.92	0.58	83.62	1.64
2	18.71	0.05	14.25	0.10
3	60.41	0.25	81.49	5.81
Median	45.92	0.25	81.49	1.64
Transposon alone
4	63.73	0.60	48.00	0.36
5	27.17	0.34	47.24	3.22
6	42.87	0.00	48.01	0.15
7	55.02	0.63	39.41	0.66
Median	48.95	0.47	47.60	0.51
Transposon + SB100X
8	64.61	1.32	70.81	2.59
9	23.29	2.92	23.69	13.43
10	8.68	1.61	33.08	0.49
11	45.95	7.32	26.85	7.11
12	29.39	7.62	18.94	5.89
13	22.74	4.02	47.99	3.32
14	70.73	27.14	69.99	18.11
15	76.82	1.56	25.39	7.37
16	47.42	8.25	52.95	6.22
17	39.42	2.65	57.30	3.99
18	16.37	28.96	18.07	34.50
19	68.73	0.57	43.29	4.28
20	78.67	0.69	69.83	5.29
21	55.57	1.06	72.16	2.12
Median	46.69	2.79	45.64	5.59

hCD45 indicates human CD45.