Distribution of cytogenetic abnormalities in patients with PMF according to their JAK2 V617F allele burden
| JAK2V617F allele burden, percentage . | Patients with cytogenetic information available . | Cytogenetic categories . | ||
|---|---|---|---|---|
| No. . | Percentage of total . | Favorable, no. (%) . | Unfavorable, no. (%) . | |
| 0 | 26 | 44.0 | 20 (76.9) | 6 (23.0) |
| 1-25 | 8 | 47.0 | 7 (87.5) | 1 (12.5) |
| 26-50 | 17 | 39.5 | 15 (88.2) | 2 (11.7) |
| 51-75 | 17 | 54.8 | 12 (70.5) | 5 (29.4) |
| 76-100 | 26 | 72.2 | 23 (88.4) | 3 (11.5) |
| Total | 94 | 50.5 | 77 (81.9) | 17 (18.1) |
| JAK2V617F allele burden, percentage . | Patients with cytogenetic information available . | Cytogenetic categories . | ||
|---|---|---|---|---|
| No. . | Percentage of total . | Favorable, no. (%) . | Unfavorable, no. (%) . | |
| 0 | 26 | 44.0 | 20 (76.9) | 6 (23.0) |
| 1-25 | 8 | 47.0 | 7 (87.5) | 1 (12.5) |
| 26-50 | 17 | 39.5 | 15 (88.2) | 2 (11.7) |
| 51-75 | 17 | 54.8 | 12 (70.5) | 5 (29.4) |
| 76-100 | 26 | 72.2 | 23 (88.4) | 3 (11.5) |
| Total | 94 | 50.5 | 77 (81.9) | 17 (18.1) |
Favorable cytogenetic category included sole deletion of 13q or 20q or trisomy 9, and a normal karyotype; unfavorable cytogenetic category included abnormalities of chromosome 5 and/or 7 and complex cytogenetics.