Cox proportional hazard models of factors independently predictive of overall survival of PMF patients
| Variable . | HR (95% CI) . | P . |
|---|---|---|
| Univariate | ||
| Age | 1.12 (1.07-1.18) | < .001 |
| Female sex | 7.58 (1.76-32.63) | .007 |
| Hemoglobin level | 0.77 (0.66-0.89) | .001 |
| Leukocyte count | 1.04 (1.02-1.05) | < .001 |
| PB blasts > 1% | 1.30 (1.16-1.45) | < .001 |
| Splenomegaly (> 15 cm LCM) | 2.41 (1.09-5.29) | .028 |
| V617F burden < 25% | 0.09 (0.03-0.32) | < .001 |
| Multivariate | ||
| Age | 1.21 (1.08-1.34) | .001 |
| PB blasts > 1% | 1.57 (1.13-2.16) | .022 |
| V617F burden < 25% | 0.023 (0.002-0.24) | .002 |
| Variable . | HR (95% CI) . | P . |
|---|---|---|
| Univariate | ||
| Age | 1.12 (1.07-1.18) | < .001 |
| Female sex | 7.58 (1.76-32.63) | .007 |
| Hemoglobin level | 0.77 (0.66-0.89) | .001 |
| Leukocyte count | 1.04 (1.02-1.05) | < .001 |
| PB blasts > 1% | 1.30 (1.16-1.45) | < .001 |
| Splenomegaly (> 15 cm LCM) | 2.41 (1.09-5.29) | .028 |
| V617F burden < 25% | 0.09 (0.03-0.32) | < .001 |
| Multivariate | ||
| Age | 1.21 (1.08-1.34) | .001 |
| PB blasts > 1% | 1.57 (1.13-2.16) | .022 |
| V617F burden < 25% | 0.023 (0.002-0.24) | .002 |