Table 3 Univariate analyses of acute... | American Society of Hematology

Table 3

Univariate analyses of acute GVHD and survival according to HLA disparity in the GVH direction

No. of HLA mismatches in the GVH direction	Acute GVHD II-IV			2-year overall survival
No. of HLA mismatches in the GVH direction	n	Cumulative incidence, %	P	n	Survival rate, %	P
HLA-A, -B, -DR (antigen)			.08			.5
0 + 1	50	33		59	36
2	84	48		104	35
HLA-A, -B (class I antigen)			.5			.2
0	22	36		24	54
1	80	42		96	32
2	32	46		43	32
HLA-DR (class II antigen)			.5			.9
0	71	38		91	32
1 + 2	63	47		72	38
HLA-A, -B (antigen), -DR (allele)			.4			1.0
0 + 1	25	32		29	38
2	48	51		60	38
3 + 4	30	44		38	39
HLA-A, -B, -DR (allele)			.3			.4
0 + 1	15	27		16	56
2	35	49		41	37
3 + 4 + 5	36	51		50	35

No. of HLA mismatches in the GVH direction	Acute GVHD II-IV			2-year overall survival
No. of HLA mismatches in the GVH direction	n	Cumulative incidence, %	P	n	Survival rate, %	P
HLA-A, -B, -DR (antigen)			.08			.5
0 + 1	50	33		59	36
2	84	48		104	35
HLA-A, -B (class I antigen)			.5			.2
0	22	36		24	54
1	80	42		96	32
2	32	46		43	32
HLA-DR (class II antigen)			.5			.9
0	71	38		91	32
1 + 2	63	47		72	38
HLA-A, -B (antigen), -DR (allele)			.4			1.0
0 + 1	25	32		29	38
2	48	51		60	38
3 + 4	30	44		38	39
HLA-A, -B, -DR (allele)			.3			.4
0 + 1	15	27		16	56
2	35	49		41	37
3 + 4 + 5	36	51		50	35