Patient characteristics according to treatment group
| Characteristic . | MEL200 (N = 149) . | MEL100 (N = 149) . |
|---|---|---|
| Male sex, no. (%) | 78 (48) | 78 (48) |
| Median age, y (range) | 58 (33-65) | 57 (32-65) |
| Age, y, no. (%) | ||
| 60-65 | 67 (45) | 51 (34) |
| 55-59 | 37 (25) | 37 (25) |
| 50-54 | 21 (14) | 38 (25) |
| Younger than 50 | 24 (16) | 23 (15) |
| Stage, no. (%) | ||
| IIA | 42 (28) | 46 (31) |
| IIB | 5 (3) | 3 (2) |
| IIIA | 94 (63) | 90 (60) |
| IIIB | 8 (5) | 10 (7) |
| M-protein class, no. (%) | ||
| IgG | 88 (59) | 83 (56) |
| IgA | 33 (22) | 42 (28) |
| Bence Jones protein | 27 (18) | 21 (14) |
| Other | 0 (0) | 3 (2) |
| Hemoglobin | ||
| No. of patients | 77 | 81 |
| Median, g/dL | 11.0 | 11.4 |
| Range, g/dL | 6.2-15.3 | 5.2-16.4 |
| Serum creatinine | ||
| No. of patients | 149 | 149 |
| Median, mg/dL | 0.8 | 0.8 |
| Range, mg/dL | 0.6-2.4 | 0.35-2.5 |
| Serum calcemia | ||
| No. of patients | 74 | 72 |
| Median, mM | 2.29 | 2.36 |
| Range, mM | 1.25-3.22 | 1.75-3.12 |
| International Staging System | ||
| 1 | 60 (40) | 71 (48) |
| 2 | 49 (33) | 38 (25) |
| 3 | 18 (12) | 23 (15) |
| Data missing | 22 (15) | 17 (11) |
| Serum β2-microglobulin | ||
| No. of patients | 127 | 132 |
| Median, mg/L | 3.03 | 2.94 |
| Range, mg/L | 0.2-17.35 | 0.17-38.2 |
| β2-Microglobulin, no. (%) | ||
| 3.5 mg/L or less | 73 (49) | 84 (57) |
| More than 3.5 mg/L | 54 (36) | 48 (32) |
| Data missing | 22 (15) | 17 (11) |
| Albumin | ||
| No. of patients | 63 | 59 |
| Median, g/dL | 3.5 | 3.6 |
| Range, g/dL | 1.5-4.8 | 2.2-5.2 |
| Plasma C-reactive protein | ||
| No. of patients | 119 | 121 |
| Median, mg/L | 0.90 | 0.6 |
| Range, mg/L | 0.005-43 | 0.002-63 |
| Characteristic . | MEL200 (N = 149) . | MEL100 (N = 149) . |
|---|---|---|
| Male sex, no. (%) | 78 (48) | 78 (48) |
| Median age, y (range) | 58 (33-65) | 57 (32-65) |
| Age, y, no. (%) | ||
| 60-65 | 67 (45) | 51 (34) |
| 55-59 | 37 (25) | 37 (25) |
| 50-54 | 21 (14) | 38 (25) |
| Younger than 50 | 24 (16) | 23 (15) |
| Stage, no. (%) | ||
| IIA | 42 (28) | 46 (31) |
| IIB | 5 (3) | 3 (2) |
| IIIA | 94 (63) | 90 (60) |
| IIIB | 8 (5) | 10 (7) |
| M-protein class, no. (%) | ||
| IgG | 88 (59) | 83 (56) |
| IgA | 33 (22) | 42 (28) |
| Bence Jones protein | 27 (18) | 21 (14) |
| Other | 0 (0) | 3 (2) |
| Hemoglobin | ||
| No. of patients | 77 | 81 |
| Median, g/dL | 11.0 | 11.4 |
| Range, g/dL | 6.2-15.3 | 5.2-16.4 |
| Serum creatinine | ||
| No. of patients | 149 | 149 |
| Median, mg/dL | 0.8 | 0.8 |
| Range, mg/dL | 0.6-2.4 | 0.35-2.5 |
| Serum calcemia | ||
| No. of patients | 74 | 72 |
| Median, mM | 2.29 | 2.36 |
| Range, mM | 1.25-3.22 | 1.75-3.12 |
| International Staging System | ||
| 1 | 60 (40) | 71 (48) |
| 2 | 49 (33) | 38 (25) |
| 3 | 18 (12) | 23 (15) |
| Data missing | 22 (15) | 17 (11) |
| Serum β2-microglobulin | ||
| No. of patients | 127 | 132 |
| Median, mg/L | 3.03 | 2.94 |
| Range, mg/L | 0.2-17.35 | 0.17-38.2 |
| β2-Microglobulin, no. (%) | ||
| 3.5 mg/L or less | 73 (49) | 84 (57) |
| More than 3.5 mg/L | 54 (36) | 48 (32) |
| Data missing | 22 (15) | 17 (11) |
| Albumin | ||
| No. of patients | 63 | 59 |
| Median, g/dL | 3.5 | 3.6 |
| Range, g/dL | 1.5-4.8 | 2.2-5.2 |
| Plasma C-reactive protein | ||
| No. of patients | 119 | 121 |
| Median, mg/L | 0.90 | 0.6 |
| Range, mg/L | 0.005-43 | 0.002-63 |