Patient and disease characteristics of the study population
| Parameter . | Frequency, no. (%) . |
|---|---|
| Age, y | |
| Less than 18 | 172 (29.5) |
| 18-35 | 288 (49.3) |
| More than 35 | 124 (21.2) |
| Male:female | 291 (49.8):293 (50.2) |
| Splenectomized | 325 (55.7) |
| Serum ferritin, μg/L | |
| Less than 1000 | 376 (64.4) |
| 1000-2500 | 179 (30.6) |
| More than 2500 | 29 (5) |
| Treatment | |
| Hydroxyurea | 202 (34.6) |
| Occasional transfusion | 143 (24.5) |
| Regular transfusion | 302 (51.7) |
| Iron chelation | 336 (47.5) |
| Complications | |
| Osteoporosis | 134 (22.9) |
| EMH | 124 (21.2) |
| Hypogonadism | 101 (17.3) |
| Cholelithiasis | 100 (17.1) |
| Thrombosis | 82 (14) |
| PHT | 64 (11) |
| Abnormal liver function | 57 (9.8) |
| Leg ulcers | 46 (7.9) |
| Hypothyroidisim | 33 (5.7) |
| HF | 25 (4.3) |
| Diabetes mellitus | 10 (1.7) |
| Parameter . | Frequency, no. (%) . |
|---|---|
| Age, y | |
| Less than 18 | 172 (29.5) |
| 18-35 | 288 (49.3) |
| More than 35 | 124 (21.2) |
| Male:female | 291 (49.8):293 (50.2) |
| Splenectomized | 325 (55.7) |
| Serum ferritin, μg/L | |
| Less than 1000 | 376 (64.4) |
| 1000-2500 | 179 (30.6) |
| More than 2500 | 29 (5) |
| Treatment | |
| Hydroxyurea | 202 (34.6) |
| Occasional transfusion | 143 (24.5) |
| Regular transfusion | 302 (51.7) |
| Iron chelation | 336 (47.5) |
| Complications | |
| Osteoporosis | 134 (22.9) |
| EMH | 124 (21.2) |
| Hypogonadism | 101 (17.3) |
| Cholelithiasis | 100 (17.1) |
| Thrombosis | 82 (14) |
| PHT | 64 (11) |
| Abnormal liver function | 57 (9.8) |
| Leg ulcers | 46 (7.9) |
| Hypothyroidisim | 33 (5.7) |
| HF | 25 (4.3) |
| Diabetes mellitus | 10 (1.7) |