Differentially expressed genes in BCR-ABL− and MLL-AF4− patients between BAALC expression groups (t3 vs t1)
| Gene symbol . | Description . | Fold change . |
|---|---|---|
| Genes overexpressed in the high BAALC group (t3 vs t1) | ||
| BAALC* | Brain and acute leukemia, cytoplasmic | 22.8 |
| ARHGEF17* | Rho guanine nucleotide exchange factor (GEF) 17 | 10.2 |
| KCNK12 | Potassium channel, subfamily K, member 12 | 8.2 |
| IGJ | Immunoglobulin J polypeptide, linker protein for immunoglobulin-α and -μ polypeptides | 7.7 |
| LOC285628 | Hypothetical protein LOC285628 | 6.3 |
| STARD13 | Start domain containing 13 | 6.0 |
| LOC26010 | Viral DNA polymerase-transactivated protein 6 | 5.6 |
| SEMA6A | Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 5.6 |
| MMP28 | Matrix metallopeptidase 28 | 5.2 |
| SDC2 | Syndecan 2 | 5.0 |
| STYK1 | Serine/threonine/tyrosine kinase 1 | 5.0 |
| KLF9* | Kruppel-like factor 9 | 4.8 |
| CD34 | CD34 antigen | 4.1 |
| CD99* | CD99 antigen | 3.9 |
| CYTL1 | Cytokine-like 1 | 3.9 |
| LOC144481 | Hypothetical protein LOC144481 | 3.8 |
| NRN | Neuritin 1 | 3.8 |
| SESN1* | Sestrin 1 | 3.7 |
| EMP1* | Epithelial membrane protein 1 | 3.7 |
| NUDT4 | NUDIX (nucleoside diphosphate-linked moiety X)-type motif 4 | 3.5 |
| TBXA2R | Thromboxane A2 receptor | 3.5 |
| TMEM156 | Transmembrane protein 156 | 3.5 |
| PPM1F* | Protein phosphatase (PP2C domain containing) | 3.3 |
| TSPAN7 | Tetraspanin 7 | 3.3 |
| MDFIC | MYOD family inhibitor domain containing | 3.3 |
| LYN | V-YES-1 Yamaguchi sarcoma viral oncogene homolog 1 | 3.1 |
| CYGB | Cytoglobin | 3.1 |
| SERPINB9 | Serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 3.1 |
| CLEC14A | C-type lectin domain family 14, member A | 3.1 |
| FHL1 | Four-and-a-half LIM domains 1 | 3.1 |
| MADD | MAP-kinase activating death domain | 3.1 |
| FZD6 | Frizzled homolog 6 (Drosophila) | 3.0 |
| Genes underexpressed in the high BAALC group (t3 vs t1) | ||
| BCL11B* | B-cell CLL/lymphoma 11B (zinc finger protein) | 5.1 |
| CAMK2D | Calcium/calmodulin-dependent protein kinase (CAM kinase) IIδ | 4.6 |
| CDKN1C | Cyclin-dependent kinase inhibitor 1C | 3.8 |
| FLJ34870 | Hypothetical protein FLJ34870 | 3.6 |
| MGC10744* | Transmembrane protein 107 | 3.4 |
| COL27A1 | Collagen, type 27, α 1 | 3.3 |
| GATA3 | GATA binding protein 3 | 3.2 |
| AEBP1 | AE binding protein 1 | 3.1 |
| GLT1D1 | Glycosyltransferase 1 domain containing 1 | 3.1 |
| PYCARD | PYD and CARD domain containing | 3.0 |
| RGS2 | Regulator of G-protein signaling 2, 24 kDa | 3.0 |
| Gene symbol . | Description . | Fold change . |
|---|---|---|
| Genes overexpressed in the high BAALC group (t3 vs t1) | ||
| BAALC* | Brain and acute leukemia, cytoplasmic | 22.8 |
| ARHGEF17* | Rho guanine nucleotide exchange factor (GEF) 17 | 10.2 |
| KCNK12 | Potassium channel, subfamily K, member 12 | 8.2 |
| IGJ | Immunoglobulin J polypeptide, linker protein for immunoglobulin-α and -μ polypeptides | 7.7 |
| LOC285628 | Hypothetical protein LOC285628 | 6.3 |
| STARD13 | Start domain containing 13 | 6.0 |
| LOC26010 | Viral DNA polymerase-transactivated protein 6 | 5.6 |
| SEMA6A | Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 5.6 |
| MMP28 | Matrix metallopeptidase 28 | 5.2 |
| SDC2 | Syndecan 2 | 5.0 |
| STYK1 | Serine/threonine/tyrosine kinase 1 | 5.0 |
| KLF9* | Kruppel-like factor 9 | 4.8 |
| CD34 | CD34 antigen | 4.1 |
| CD99* | CD99 antigen | 3.9 |
| CYTL1 | Cytokine-like 1 | 3.9 |
| LOC144481 | Hypothetical protein LOC144481 | 3.8 |
| NRN | Neuritin 1 | 3.8 |
| SESN1* | Sestrin 1 | 3.7 |
| EMP1* | Epithelial membrane protein 1 | 3.7 |
| NUDT4 | NUDIX (nucleoside diphosphate-linked moiety X)-type motif 4 | 3.5 |
| TBXA2R | Thromboxane A2 receptor | 3.5 |
| TMEM156 | Transmembrane protein 156 | 3.5 |
| PPM1F* | Protein phosphatase (PP2C domain containing) | 3.3 |
| TSPAN7 | Tetraspanin 7 | 3.3 |
| MDFIC | MYOD family inhibitor domain containing | 3.3 |
| LYN | V-YES-1 Yamaguchi sarcoma viral oncogene homolog 1 | 3.1 |
| CYGB | Cytoglobin | 3.1 |
| SERPINB9 | Serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 3.1 |
| CLEC14A | C-type lectin domain family 14, member A | 3.1 |
| FHL1 | Four-and-a-half LIM domains 1 | 3.1 |
| MADD | MAP-kinase activating death domain | 3.1 |
| FZD6 | Frizzled homolog 6 (Drosophila) | 3.0 |
| Genes underexpressed in the high BAALC group (t3 vs t1) | ||
| BCL11B* | B-cell CLL/lymphoma 11B (zinc finger protein) | 5.1 |
| CAMK2D | Calcium/calmodulin-dependent protein kinase (CAM kinase) IIδ | 4.6 |
| CDKN1C | Cyclin-dependent kinase inhibitor 1C | 3.8 |
| FLJ34870 | Hypothetical protein FLJ34870 | 3.6 |
| MGC10744* | Transmembrane protein 107 | 3.4 |
| COL27A1 | Collagen, type 27, α 1 | 3.3 |
| GATA3 | GATA binding protein 3 | 3.2 |
| AEBP1 | AE binding protein 1 | 3.1 |
| GLT1D1 | Glycosyltransferase 1 domain containing 1 | 3.1 |
| PYCARD | PYD and CARD domain containing | 3.0 |
| RGS2 | Regulator of G-protein signaling 2, 24 kDa | 3.0 |
Gene was represented by more than one probe set. The fold change corresponds to the mean value of all probe sets.