Most frequent AEs occurring in patients treated with dexamethasone alone, dexamethasone plus rituximab, or dexamethasone plus rituximab salvage therapy
| Therapy . | Patients, n (%) . | ||
|---|---|---|---|
| Dexamethasone . | Dexamethasone plus rituximab . | Dexamethasone plus rituximab salvage therapy . | |
| Safety population | 52 | 49 | 27 |
| Patients with any AE | 26 (50) | 37 (76) | 18 (67) |
| Patients with serious AEs | 1 (2) | 3 (6) | 3 (11) |
| List of serious AEs | |||
| Hemorrhagic disorder | 0 | 1 | 0 |
| Platelet count decreased | 0 | 0 | 1 |
| Supraventricular tachycardia | 0 | 1 | 0 |
| Pneumonia | 0 | 1 | 0 |
| Rib fracture | 1 | 0 | 0 |
| Convulsion | 0 | 0 | 1 |
| Transitory ischemic attack | 0 | 0 | 1 |
| Patients with grade 3-4 AEs | 1 (2) | 5 (10) | 6 (22) |
| List of AEs | |||
| Hemorrhagic disorder | 0 | 1 | 0 |
| Platelet count decreased | 1 | 0 | 3 |
| Supraventricular tachycardia | 0 | 1 | 0 |
| Fever | 0 | 2 | 0 |
| Hypersensitivity | 0 | 1 | 0 |
| Pneumonia | 0 | 1 | 0 |
| Transaminases increased | 0 | 2 | 0 |
| Arthralgia | 0 | 0 | 1 |
| Convulsion | 0 | 0 | 1 |
| Nephrolithiasis | 0 | 0 | 1 |
| Patients with grade 3-4 AEs related to study drug | 0 | 2 (4) | 2 (7) |
| List of AEs | |||
| Supraventricular tachycardia | 0 | 1 | 0 |
| Fever | 0 | 1 | 0 |
| Pneumonia | 0 | 1 | 0 |
| Transaminases increased | 0 | 1 | 0 |
| Arthralgia | 0 | 0 | 1 |
| Convulsion | 0 | 0 | 1 |
| Therapy . | Patients, n (%) . | ||
|---|---|---|---|
| Dexamethasone . | Dexamethasone plus rituximab . | Dexamethasone plus rituximab salvage therapy . | |
| Safety population | 52 | 49 | 27 |
| Patients with any AE | 26 (50) | 37 (76) | 18 (67) |
| Patients with serious AEs | 1 (2) | 3 (6) | 3 (11) |
| List of serious AEs | |||
| Hemorrhagic disorder | 0 | 1 | 0 |
| Platelet count decreased | 0 | 0 | 1 |
| Supraventricular tachycardia | 0 | 1 | 0 |
| Pneumonia | 0 | 1 | 0 |
| Rib fracture | 1 | 0 | 0 |
| Convulsion | 0 | 0 | 1 |
| Transitory ischemic attack | 0 | 0 | 1 |
| Patients with grade 3-4 AEs | 1 (2) | 5 (10) | 6 (22) |
| List of AEs | |||
| Hemorrhagic disorder | 0 | 1 | 0 |
| Platelet count decreased | 1 | 0 | 3 |
| Supraventricular tachycardia | 0 | 1 | 0 |
| Fever | 0 | 2 | 0 |
| Hypersensitivity | 0 | 1 | 0 |
| Pneumonia | 0 | 1 | 0 |
| Transaminases increased | 0 | 2 | 0 |
| Arthralgia | 0 | 0 | 1 |
| Convulsion | 0 | 0 | 1 |
| Nephrolithiasis | 0 | 0 | 1 |
| Patients with grade 3-4 AEs related to study drug | 0 | 2 (4) | 2 (7) |
| List of AEs | |||
| Supraventricular tachycardia | 0 | 1 | 0 |
| Fever | 0 | 1 | 0 |
| Pneumonia | 0 | 1 | 0 |
| Transaminases increased | 0 | 1 | 0 |
| Arthralgia | 0 | 0 | 1 |
| Convulsion | 0 | 0 | 1 |
AE indicates adverse event.