Type of injury/surgical procedure related to outcome
| Surgical procedures . | Number of patients . | Seroconversion . | HIT cases . | Thromboses . | |||||
|---|---|---|---|---|---|---|---|---|---|
| Proximal or PE . | Distal . | ||||||||
| UFH . | LMWH . | UFH . | LMWH . | UFH . | LMWH . | UFH . | LMWH . | ||
| Major surgical procedures | |||||||||
| Fracture humerus | 63 | 5 | 1 | — | — | — | 1* | 1 | 1 |
| Fracture hip/pelvis | 54 | 3 | 2 | — | — | 1 | 3 | 3 | 2 |
| Fracture femur | 59 | 5 | 2 | 2 | 1 | 5*,†,† | 7† | 1 | 4 |
| Knee endoprothesis | 3 | 1 | — | 1 | — | — | — | 1† | — |
| Fracture head of tibia | 15 | 2 | — | 1 | — | 2† | — | 1 | — |
| Fracture tibia | 30 | 1 | — | — | — | — | — | — | 1 |
| Total major surgical procedures (95% CI) | 224 | 17/100, 17.0%(9.6-24.4) | 5/124, 4.0%(0.6-7.4) | 4/100, 4.0%(0.2-7.8) | 1/124, 0.8%(0.0-2.4) | 8/100, 8.0%(2.7-13.3) | 11/124, 8.9%(6.0-16.0) | 7/100, 7.0%(2.0-12.0) | 8/124, 6.5%(2.2-10.8) |
| P = .001 | P = .18 | P = .82 | P = .87 | ||||||
| Minor surgical procedures | |||||||||
| Lower arm/hand | 123 | 1 | — | — | — | — | — | — | — |
| Shoulder | 21 | — | — | — | — | — | — | — | — |
| Knee (eg, cruciate ligament rupture) | 23 | — | — | — | — | — | — | 1 | — |
| Fracture ankle joint | 57 | 2 | — | — | — | — | — | 2 | 1 |
| Foot | 19 | — | — | — | — | 1 | — | — | — |
| Removal of metal | 35 | — | — | — | — | — | — | — | — |
| Fracture spine | 14 | — | — | — | — | — | — | — | 1 |
| Tendon injury | 26 | — | — | — | — | — | — | — | 2 |
| Others | 19 | — | — | — | — | — | — | — | — |
| Total minor surgical procedures | 337 | 3/189 (1.6%) | 0/148 (0.0%) | 0/189 (0.0%) | 0/148 (0.0%) | 1/189 (0.53%) | 0/148 (0.0%) | 3/189 (1.6%) | 4/148 (2.7%) |
| Total no surgical procedures | 53 | 1/27 (3.7%) | 0/26 (0.0%) | 0/27 (0.0%) | 0/26 (0.0%) | 0/27 (0.0%) | 0/26 (0.0%) | 2/27 (7.4%) | 0/26 (0.0%) |
| Total (95% CI) | 614 | 21/316, 6.6% (3.9-9.3) | 5/298, 1.7%(0.2-3.2) | 4/316, 1.3%(0.1-2.5) | 1/298, 0.3%(0.0-0.9) | 9/316, 2.8%(1.0-4.6) | 11/298, 3.7%(1.6-5.8) | 12/316, 3.8%(1.7-5.9) | 12/298, 4.0%(1.8-6.2) |
| P = .002 | P = .37 | P = .56 | P = .88 | ||||||
| Surgical procedures . | Number of patients . | Seroconversion . | HIT cases . | Thromboses . | |||||
|---|---|---|---|---|---|---|---|---|---|
| Proximal or PE . | Distal . | ||||||||
| UFH . | LMWH . | UFH . | LMWH . | UFH . | LMWH . | UFH . | LMWH . | ||
| Major surgical procedures | |||||||||
| Fracture humerus | 63 | 5 | 1 | — | — | — | 1* | 1 | 1 |
| Fracture hip/pelvis | 54 | 3 | 2 | — | — | 1 | 3 | 3 | 2 |
| Fracture femur | 59 | 5 | 2 | 2 | 1 | 5*,†,† | 7† | 1 | 4 |
| Knee endoprothesis | 3 | 1 | — | 1 | — | — | — | 1† | — |
| Fracture head of tibia | 15 | 2 | — | 1 | — | 2† | — | 1 | — |
| Fracture tibia | 30 | 1 | — | — | — | — | — | — | 1 |
| Total major surgical procedures (95% CI) | 224 | 17/100, 17.0%(9.6-24.4) | 5/124, 4.0%(0.6-7.4) | 4/100, 4.0%(0.2-7.8) | 1/124, 0.8%(0.0-2.4) | 8/100, 8.0%(2.7-13.3) | 11/124, 8.9%(6.0-16.0) | 7/100, 7.0%(2.0-12.0) | 8/124, 6.5%(2.2-10.8) |
| P = .001 | P = .18 | P = .82 | P = .87 | ||||||
| Minor surgical procedures | |||||||||
| Lower arm/hand | 123 | 1 | — | — | — | — | — | — | — |
| Shoulder | 21 | — | — | — | — | — | — | — | — |
| Knee (eg, cruciate ligament rupture) | 23 | — | — | — | — | — | — | 1 | — |
| Fracture ankle joint | 57 | 2 | — | — | — | — | — | 2 | 1 |
| Foot | 19 | — | — | — | — | 1 | — | — | — |
| Removal of metal | 35 | — | — | — | — | — | — | — | — |
| Fracture spine | 14 | — | — | — | — | — | — | — | 1 |
| Tendon injury | 26 | — | — | — | — | — | — | — | 2 |
| Others | 19 | — | — | — | — | — | — | — | — |
| Total minor surgical procedures | 337 | 3/189 (1.6%) | 0/148 (0.0%) | 0/189 (0.0%) | 0/148 (0.0%) | 1/189 (0.53%) | 0/148 (0.0%) | 3/189 (1.6%) | 4/148 (2.7%) |
| Total no surgical procedures | 53 | 1/27 (3.7%) | 0/26 (0.0%) | 0/27 (0.0%) | 0/26 (0.0%) | 0/27 (0.0%) | 0/26 (0.0%) | 2/27 (7.4%) | 0/26 (0.0%) |
| Total (95% CI) | 614 | 21/316, 6.6% (3.9-9.3) | 5/298, 1.7%(0.2-3.2) | 4/316, 1.3%(0.1-2.5) | 1/298, 0.3%(0.0-0.9) | 9/316, 2.8%(1.0-4.6) | 11/298, 3.7%(1.6-5.8) | 12/316, 3.8%(1.7-5.9) | 12/298, 4.0%(1.8-6.2) |
| P = .002 | P = .37 | P = .56 | P = .88 | ||||||