Echocardiographic measures
Category/variable . | Mean (SD) . | Expected normal values . | P . |
---|---|---|---|
LV size and mass | |||
LV diastolic dimension Z-score | 2.5 (1.3) | 0 (−2 to 2) | < .001 |
LV mass index, g/m2.7 | 44.9 (10.7) | 26-39* | < .001 |
Relative wall thickness | 0.27 (0.04) | < 0.41 | .7 |
LV systolic function | |||
Shortening fraction | 0.37 (0.04) | ≥ 0.28 | .7 |
LV tissue Doppler | |||
E′ | 15.7 (3.4) | 16.5 (5.3) | .1 |
A′ | 4.8 (1.2) | 6.4 (1.9) | < .001 |
S′ | 8.0 (2.1) | 9.3 (3.4) | < .001 |
E/E′ | 7.2 (2.2) | 6.1 (2.4) | .002 |
MPI index | 0.45 (0.09) | 0.35 (0.09) | < .001 |
Septal tissue Doppler | |||
E′ | 11.7 (2.0) | 12.6 (3.4) | .004 |
A′ | 5.6 (1.9) | 6.1 (1.6) | .1 |
S′ | 7.6 (1.1) | 7.6 (1.9) | .8 |
MPI index | 0.47 (0.08) | 0.35 (0.09) | < .001 |
Category/variable . | Mean (SD) . | Expected normal values . | P . |
---|---|---|---|
LV size and mass | |||
LV diastolic dimension Z-score | 2.5 (1.3) | 0 (−2 to 2) | < .001 |
LV mass index, g/m2.7 | 44.9 (10.7) | 26-39* | < .001 |
Relative wall thickness | 0.27 (0.04) | < 0.41 | .7 |
LV systolic function | |||
Shortening fraction | 0.37 (0.04) | ≥ 0.28 | .7 |
LV tissue Doppler | |||
E′ | 15.7 (3.4) | 16.5 (5.3) | .1 |
A′ | 4.8 (1.2) | 6.4 (1.9) | < .001 |
S′ | 8.0 (2.1) | 9.3 (3.4) | < .001 |
E/E′ | 7.2 (2.2) | 6.1 (2.4) | .002 |
MPI index | 0.45 (0.09) | 0.35 (0.09) | < .001 |
Septal tissue Doppler | |||
E′ | 11.7 (2.0) | 12.6 (3.4) | .004 |
A′ | 5.6 (1.9) | 6.1 (1.6) | .1 |
S′ | 7.6 (1.1) | 7.6 (1.9) | .8 |
MPI index | 0.47 (0.08) | 0.35 (0.09) | < .001 |
Mean (SD) values for echocardiographic variables in 44 study subjects with P values based on comparison with expected normal values.37,40,41 Tissue Doppler values E′, A′, and S′ are given as centimeters per second.
MPI indicates myocardial performance index (a measure of combined systolic and diastolic function).
LV mass index normal values vary by age and sex; 27% of the reference population was African American.37