Multivariable models with oxygen saturation asleep
| Dependent variable/independent covariates . | Parameter estimate . | Standardized coefficient . | P . |
|---|---|---|---|
| LV mass index, g/m2.7 (R2 = 0.66, P < .001) | |||
| Oxygen saturation asleep, percentage | −2.1 | −0.60 | < .001 |
| Age, y | −0.73 | −0.26 | .02 |
| Systolic blood pressure percentile | 0.10 | 0.24 | .03 |
| Arousal index | 0.48 | 0.18 | .09 |
| LV diastolic dimension Z-score (R2 = 0.74, P < .001) | |||
| Oxygen saturation asleep, percentage | −0.18 | −0.43 | < .001 |
| Sleep maintenance efficiency, percentage | −0.06 | −0.48 | < .001 |
| Systolic blood pressure percentile | 0.02 | 0.42 | .001 |
| Heart rate | −0.04 | −0.38 | .006 |
| Oxygen desaturation index | 0.03 | 0.32 | .007 |
| Body mass index percentile | −0.01 | −0.25 | .02 |
| Arginine-ornithine ratio | 0.22 | 0.22 | .05 |
| LV E/E′ (R2 = 0.4, P < .001) | |||
| Oxygen saturation asleep, percentage | −0.46 | −0.63 | < .001 |
| Oxygen desaturation index | −0.04 | −0.31 | .03 |
| Dependent variable/independent covariates . | Parameter estimate . | Standardized coefficient . | P . |
|---|---|---|---|
| LV mass index, g/m2.7 (R2 = 0.66, P < .001) | |||
| Oxygen saturation asleep, percentage | −2.1 | −0.60 | < .001 |
| Age, y | −0.73 | −0.26 | .02 |
| Systolic blood pressure percentile | 0.10 | 0.24 | .03 |
| Arousal index | 0.48 | 0.18 | .09 |
| LV diastolic dimension Z-score (R2 = 0.74, P < .001) | |||
| Oxygen saturation asleep, percentage | −0.18 | −0.43 | < .001 |
| Sleep maintenance efficiency, percentage | −0.06 | −0.48 | < .001 |
| Systolic blood pressure percentile | 0.02 | 0.42 | .001 |
| Heart rate | −0.04 | −0.38 | .006 |
| Oxygen desaturation index | 0.03 | 0.32 | .007 |
| Body mass index percentile | −0.01 | −0.25 | .02 |
| Arginine-ornithine ratio | 0.22 | 0.22 | .05 |
| LV E/E′ (R2 = 0.4, P < .001) | |||
| Oxygen saturation asleep, percentage | −0.46 | −0.63 | < .001 |
| Oxygen desaturation index | −0.04 | −0.31 | .03 |
Multivariable models of LV mass index, LV diastolic dimension Z-score, and LV E/E′ with oxygen saturation asleep, other sleep variables, and confounding independent variables for 44 study subjects. Sleep variables as potential independent variables: arousal index, sleep maintenance efficiency, OAHI at 3% desaturation, average oxygen saturation asleep, and oxygen desaturation index. Potential confounding variables evaluated: hemoglobin, LDH, arginine-ornithine ratio, age, heart rate, systolic and diastolic blood pressure percentiles, and body mass index percentile.