Multivariable models with waking oxygen saturation
| Dependent variable/independent and confounding variables . | Parameter estimate . | Standardized coefficient . | P . |
|---|---|---|---|
| LV mass index, g/m2.7 (R2 = 0.62, P < .001) | |||
| Waking oxygen saturation, percentage | −1.6 | −0.57 | < .001 |
| Age, y | −0.78 | −0.28 | .02 |
| Arousal index | 0.65 | 0.24 | .04 |
| Systolic blood pressure percentile | 0.1 | 0.23 | .05 |
| LV diastolic dimension Z-score (R2 = 0.72, P < .001) | |||
| Sleep maintenance efficiency, percentage | −0.07 | −0.58 | < .001 |
| Waking oxygen saturation, percentage | −0.13 | −0.42 | < .001 |
| Heart rate | −0.04 | −0.4 | .006 |
| Arousal index | 0.09 | 0.28 | .02 |
| Systolic blood pressure percentile | 0.02 | 0.31 | .02 |
| Hemoglobin, g/dL | −0.3 | −0.28 | .03 |
| LV E/E′ (R2 = 0.31, P = .002) | |||
| Waking oxygen saturation, percentage | −0.31 | −0.56 | < .001 |
| Oxygen desaturation index | −0.05 | −0.32 | .04 |
| Dependent variable/independent and confounding variables . | Parameter estimate . | Standardized coefficient . | P . |
|---|---|---|---|
| LV mass index, g/m2.7 (R2 = 0.62, P < .001) | |||
| Waking oxygen saturation, percentage | −1.6 | −0.57 | < .001 |
| Age, y | −0.78 | −0.28 | .02 |
| Arousal index | 0.65 | 0.24 | .04 |
| Systolic blood pressure percentile | 0.1 | 0.23 | .05 |
| LV diastolic dimension Z-score (R2 = 0.72, P < .001) | |||
| Sleep maintenance efficiency, percentage | −0.07 | −0.58 | < .001 |
| Waking oxygen saturation, percentage | −0.13 | −0.42 | < .001 |
| Heart rate | −0.04 | −0.4 | .006 |
| Arousal index | 0.09 | 0.28 | .02 |
| Systolic blood pressure percentile | 0.02 | 0.31 | .02 |
| Hemoglobin, g/dL | −0.3 | −0.28 | .03 |
| LV E/E′ (R2 = 0.31, P = .002) | |||
| Waking oxygen saturation, percentage | −0.31 | −0.56 | < .001 |
| Oxygen desaturation index | −0.05 | −0.32 | .04 |
Multivariable models of LV diastolic dimension Z-score and LV mass index with waking oxygen saturation, sleep variables, and confounding independent variables for 44 study subjects. Sleep variables as potential independent variables: arousal index, sleep maintenance efficiency, OAHI at 3% desaturation, and oxygen desaturation index. Potential confounding variables evaluated: hemoglobin, LDH, arginine-ornithine ratio, age, heart rate, systolic and diastolic blood pressure percentiles, and body mass index percentile.