Correlation between levels of APM components in transformed plasma cells of MGUS patients at the time of BM sampling and changes in serum M component during the course of 24 months
Component . | Positive cells, % . | MESF units . | ||
---|---|---|---|---|
r . | P . | r . | P . | |
δ | −0.596 | .001 | −0.342 | .043 |
LMP2 | −0.321 | .021 | −0.224 | .049 |
LMP10 | −0.442 | .003 | −0.381 | .045 |
TAP1 | −0.317 | n.s. | −0.338 | .026 |
Calnexin | 0.586 | .009 | 0.436 | .024 |
Calreticulin | 0.539 | .006 | 0.399 | .028 |
Tapasin | 0.441 | .012 | 0.340 | .039 |
β2-m | 0.300 | n.s. | 0.589 | .001 |
HLA class I | 0.233 | n.s. | 0.463 | .006 |
Component . | Positive cells, % . | MESF units . | ||
---|---|---|---|---|
r . | P . | r . | P . | |
δ | −0.596 | .001 | −0.342 | .043 |
LMP2 | −0.321 | .021 | −0.224 | .049 |
LMP10 | −0.442 | .003 | −0.381 | .045 |
TAP1 | −0.317 | n.s. | −0.338 | .026 |
Calnexin | 0.586 | .009 | 0.436 | .024 |
Calreticulin | 0.539 | .006 | 0.399 | .028 |
Tapasin | 0.441 | .012 | 0.340 | .039 |
β2-m | 0.300 | n.s. | 0.589 | .001 |
HLA class I | 0.233 | n.s. | 0.463 | .006 |
Levels of APM components were expressed as both percentage of cells staining positively and MESF units. Only APM components that had at least 1 significant correlation are shown; Spearman rank test.
β2-m indicates β2-microglobulin; BM, bone marrow; HLA, human leukocyte antigen; and MESF, molecular equivalents of soluble fluorochrome. Other abbreviations as in Table 1.