Table 1

HbS genotype frequencies in cases and controls

Overall, no. (%)HbAA, no. (%)HbAS, no. (%)SCA, no. (%)
Controls 1480 (100) 1252 (84.59) 218 (14.73) 10 (0.80) 
Uncomplicated malaria 807 (100) 770 (95.42) 35 (4.34) 2 (0.26)* 
Severe malaria 1393 (100) 1357 (97.42) 31 (2.23) 5 (0.37) 
Nonmalaria illnesses 743 (100) 636 (85.60) 86 (11.57) 21 (3.30) 
Bacteremia 1497 (100) 1280 (85.50) 134 (8.95) 83 (6.48)§ 
Total 5919 (100) 5295 (89.46) 504 (8.51) 120 (2.27) 
Overall, no. (%)HbAA, no. (%)HbAS, no. (%)SCA, no. (%)
Controls 1480 (100) 1252 (84.59) 218 (14.73) 10 (0.80) 
Uncomplicated malaria 807 (100) 770 (95.42) 35 (4.34) 2 (0.26)* 
Severe malaria 1393 (100) 1357 (97.42) 31 (2.23) 5 (0.37) 
Nonmalaria illnesses 743 (100) 636 (85.60) 86 (11.57) 21 (3.30) 
Bacteremia 1497 (100) 1280 (85.50) 134 (8.95) 83 (6.48)§ 
Total 5919 (100) 5295 (89.46) 504 (8.51) 120 (2.27) 

Overall, the diagnosis of SCA was already established at the time of admission in 16 patients: *1, †1, ‡2, and §12.

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