Table 1 Hemodynamic parameters of SCD... | American Society of Hematology

Table 1

Hemodynamic parameters of SCD mice treated in protocol 1

Treatments	Mice, n	Weight, g*	Venules, n	Venular diameter, μ*	Centerline velocity, mm/s*	Wall shear rate, s⁻*	WBC count, 10³/μL*
PBS	10	25.9 ± 0.8	42	21.3 ± 0.5	1.4 ± 0.1†	696 ± 48†	14.6 ± 3.3‡
GMI-1070	5	26.9 ± 0.3	51	20.9 ± 0.4	3.1 ± 0.2	1573 ± 117	11.7 ± 1.5§
αPsel + αEsel	5	26.3 ± 0.7	58	20.7 ± 0.4	3.1 ± 0.3	1578 ± 130	24.3 ± 1.2

Treatments	Mice, n	Weight, g*	Venules, n	Venular diameter, μ*	Centerline velocity, mm/s*	Wall shear rate, s⁻*	WBC count, 10³/μL*
PBS	10	25.9 ± 0.8	42	21.3 ± 0.5	1.4 ± 0.1†	696 ± 48†	14.6 ± 3.3‡
GMI-1070	5	26.9 ± 0.3	51	20.9 ± 0.4	3.1 ± 0.2	1573 ± 117	11.7 ± 1.5§
αPsel + αEsel	5	26.3 ± 0.7	58	20.7 ± 0.4	3.1 ± 0.3	1578 ± 130	24.3 ± 1.2

SCD indicates sickle cell disease; WBC, white blood cell; and PBS, phosphate-buffered saline.

Data are presented as mean ± SEM.

P < .001 compared with GMI-1070.

P < .05 compared with αPsel + αEsel.

P < .01 compared with αPsel + αEsel.