Table 1

Summary of phosphoproteomic data

Phosphoproteomic summaryNo.
Identified phosphoproteins 500 
Regulated phosphoproteins 207 
Identified phosphopeptides 796 
Regulated phosphopeptides 247 
Kinase predicted phosphoproteins 78 
Kinase predicted phosphopeptides 103 
Kinase predicted phosphosites  
    PKA 41 
    CAMKII 18 
    PKB/Akt 14 
    GSK3 15 
    CK2 14 
    CK1 11 
    ERK 
    PKC 
    Cdk5 
    PAK1 
    MAPKAPK2 
    p38 
    PKG 
    AurB 
    Cdc2 
    Clk2 
    MKK3 
    MKK6 
    Mnk1 
    PKD 
    PLK1 
Phosphoproteomic summaryNo.
Identified phosphoproteins 500 
Regulated phosphoproteins 207 
Identified phosphopeptides 796 
Regulated phosphopeptides 247 
Kinase predicted phosphoproteins 78 
Kinase predicted phosphopeptides 103 
Kinase predicted phosphosites  
    PKA 41 
    CAMKII 18 
    PKB/Akt 14 
    GSK3 15 
    CK2 14 
    CK1 11 
    ERK 
    PKC 
    Cdk5 
    PAK1 
    MAPKAPK2 
    p38 
    PKG 
    AurB 
    Cdc2 
    Clk2 
    MKK3 
    MKK6 
    Mnk1 
    PKD 
    PLK1 

All regulated phosphosites were subjected to kinase prediction algorithms, and kinases that had been predicted for the same phosphosite by at least 2 kinase prediction algorithms were considered positive. Furthermore, kinases that have been shown to phosphorylate a specific phosphosite in vivo or in vitro were included in the predicted kinase dataset (Kinase prediction algorithms used http://scansite.mit.edu; www.networkin.info; www.phosida.com).

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