Table 1

OCT-1 activity and molecular response

Achieved MMR (% of n)Did not achieve MMR (% of n)
MNC (P = .017)   
    High OA (n = 9) 9 (100%) 0 (0%) 
    Low OA (n = 25) 14 (56%) 11 (44%) 
CD34+ (P = .026)   
    High OA (n = 17) 8 (47%) 9 (53%) 
    Low OA (n = 17) 15 (88%) 2 (12%) 
Achieved MMR (% of n)Did not achieve MMR (% of n)
MNC (P = .017)   
    High OA (n = 9) 9 (100%) 0 (0%) 
    Low OA (n = 25) 14 (56%) 11 (44%) 
CD34+ (P = .026)   
    High OA (n = 17) 8 (47%) 9 (53%) 
    Low OA (n = 17) 15 (88%) 2 (12%) 

Shown are the number of patients who did and did not achieve a major molecular response (MMR) over the first 12 months of imatinib therapy. P values were calculated using the Fisher Exact test.

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