Table 1 Candidate gene SNPs used in... | American Society of Hematology

Table 1

Candidate gene SNPs used in association studies

Gene	Protein identification	dbSNP or chromosomal location*	Cytoband	MAF
ADRA2A	α-2A-adrenergic receptor	chr10: 112 839 580†	10q24-q26	0.41
F2R	Coagulation factor II (thrombin) receptor; proteinase-activated receptor 1 (PAR-1)	rs168753	5q13	0.14
FCGR2A	IgG Fc receptor type IIa	chr1: 161 479 745‡	1q23	0.44
GNB3	Guanine nucleotide-binding protein beta-3 subunit variant	rs5443	12p13	0.45
GP1BA	Platelet glycoprotein Ib, α subunit	rs6065	17pter-p12	0.10
GP6	Platelet glycoprotein VI	rs1613662	19q13.4	0.16
ITGA2	Integrin subunit-α2	rs1126643 rs28095 rs1801106	5q11.2	0.38 0.36 0.08
ITGA2B	Integrin subunit-αIIb	rs5911	17q21.32	0.41
ITGB3	Integrin subunit-β3	rs5918	17q21.32	0.17
P2RY1	Purinogenic receptor P2Y1	rs1065776	3q25.2	0.05
P2RY12	Purinogenic receptor P2Y12	rs6809699	3q24-q25	0.14
PTGS1	Prostaglandin-endoperoxide synthase 1; cyclooxygenase-1 (COX-1)	rs3842787	9q32-q33.3	0.06
TBXA2R	Thromboxane A2 receptor	rs1131882 rs4523 rs5758	19p13.3	0.13 0.30 0.45

Gene	Protein identification	dbSNP or chromosomal location*	Cytoband	MAF
ADRA2A	α-2A-adrenergic receptor	chr10: 112 839 580†	10q24-q26	0.41
F2R	Coagulation factor II (thrombin) receptor; proteinase-activated receptor 1 (PAR-1)	rs168753	5q13	0.14
FCGR2A	IgG Fc receptor type IIa	chr1: 161 479 745‡	1q23	0.44
GNB3	Guanine nucleotide-binding protein beta-3 subunit variant	rs5443	12p13	0.45
GP1BA	Platelet glycoprotein Ib, α subunit	rs6065	17pter-p12	0.10
GP6	Platelet glycoprotein VI	rs1613662	19q13.4	0.16
ITGA2	Integrin subunit-α2	rs1126643 rs28095 rs1801106	5q11.2	0.38 0.36 0.08
ITGA2B	Integrin subunit-αIIb	rs5911	17q21.32	0.41
ITGB3	Integrin subunit-β3	rs5918	17q21.32	0.17
P2RY1	Purinogenic receptor P2Y1	rs1065776	3q25.2	0.05
P2RY12	Purinogenic receptor P2Y12	rs6809699	3q24-q25	0.14
PTGS1	Prostaglandin-endoperoxide synthase 1; cyclooxygenase-1 (COX-1)	rs3842787	9q32-q33.3	0.06
TBXA2R	Thromboxane A2 receptor	rs1131882 rs4523 rs5758	19p13.3	0.13 0.30 0.45

NCBI SNP database (dbSNP) identification number (Build 131) or flanking nucleotide sequence (when SNP has not been assigned a dbSNP number).

CATTCCCAACTCTCTCTCTCTTTTT(G/A)AAGAAAAATGCTAAGGGCAGCCCTG.

AATGGAAAATCCCAGAAATTCTCCC(A/G)TTTGGATCCCACCTTCTCCATCCCA.