Relative risk of selected fractures among patients with MGUS patients (vs matched controls), stratified by MGUS subtype
| Disease/grouping . | IgG/IgA subtype . | IgM subtype . | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5-y follow-up . | 10-y follow-up . | 5-y follow-up . | 10-y follow-up . | |||||||||
| MGUS (n = 2724) . | Ctrl (n = 10 348) . | HR* (95% CI) . | MGUS . | Ctrl . | HR* (95% CI) . | MGUS (n = 530) . | Ctrl (n = 2017) . | HR*(95% CI) . | MGUS . | Ctrl . | HR* (95% CI) . | |
| Any fracture | 276 | 685 | 1.67 (1.45-1.92) | 446 | 1214 | 1.55 (1.39-1.73) | 59 | 169 | 1.31 (0.97-1.76) | 95 | 275 | 1.30 (1.03-1.64) |
| Axial fractures† | 104 | 184 | 2.27 (1.79-2.89) | 169 | 331 | 2.12 (1.76-2.55) | 20 | 49 | 1.48 (0.88-2.50) | 30 | 71 | 1.59 (1.04-2.44) |
| Distal fractures‡ | 177 | 532 | 1.36 (1.15-1.61) | 298 | 974 | 1.27 (1.11-1.44) | 43 | 126 | 1.28 (0.91-1.81) | 70 | 223 | 1.17 (0.89-1.53) |
| Disease/grouping . | IgG/IgA subtype . | IgM subtype . | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5-y follow-up . | 10-y follow-up . | 5-y follow-up . | 10-y follow-up . | |||||||||
| MGUS (n = 2724) . | Ctrl (n = 10 348) . | HR* (95% CI) . | MGUS . | Ctrl . | HR* (95% CI) . | MGUS (n = 530) . | Ctrl (n = 2017) . | HR*(95% CI) . | MGUS . | Ctrl . | HR* (95% CI) . | |
| Any fracture | 276 | 685 | 1.67 (1.45-1.92) | 446 | 1214 | 1.55 (1.39-1.73) | 59 | 169 | 1.31 (0.97-1.76) | 95 | 275 | 1.30 (1.03-1.64) |
| Axial fractures† | 104 | 184 | 2.27 (1.79-2.89) | 169 | 331 | 2.12 (1.76-2.55) | 20 | 49 | 1.48 (0.88-2.50) | 30 | 71 | 1.59 (1.04-2.44) |
| Distal fractures‡ | 177 | 532 | 1.36 (1.15-1.61) | 298 | 974 | 1.27 (1.11-1.44) | 43 | 126 | 1.28 (0.91-1.81) | 70 | 223 | 1.17 (0.89-1.53) |