Rh phenotype prediction by genotyping with 3 molecular assays
Antigens in the RH blood group system . | Genotyping platform . | ||
---|---|---|---|
Bloodchip . | Beadchip . | PCR-SSP . | |
D | D− | NA | D−† |
C/c | C+c+* | C−c+ | C−c+ |
E/e | E−e+ | E−e+ | E−e+ |
Cx | Cx− | NA | Cx− |
Cw | Cw− | NA | Cw− |
VS | VS+ | VS+ | VS+ |
Antigens in the RH blood group system . | Genotyping platform . | ||
---|---|---|---|
Bloodchip . | Beadchip . | PCR-SSP . | |
D | D− | NA | D−† |
C/c | C+c+* | C−c+ | C−c+ |
E/e | E−e+ | E−e+ | E−e+ |
Cx | Cx− | NA | Cx− |
Cw | Cw− | NA | Cw− |
VS | VS+ | VS+ | VS+ |
NA indicates not available by platform
Although the results demonstrated a “cc” genotype, the “C+c+” phenotype is designated by this platform when associated with rs.
“D-zygosity” kit revealed 1 copy of normal Rhesus box, and one copy of hybrid Rhesus box consistent with cdes/d. RHD-CE(3–7)-D confirmed through use of “Partial-D” kit.