Response data
Response level . | Frequency . | Increase in hemoglobin level . | Decrease in IgM concentration . | |||||
---|---|---|---|---|---|---|---|---|
n . | % . | Median, g/dL . | Range, g/dL . | P . | Median, % of baseline level . | Range, % of baseline level . | P . | |
CR | 6 | 21 | 4.0 | 0.0-5.4 | < .001 | 81 | 63-91 | < .001 |
PR | 16 | 55 | 3.1 | 2.0-6.9 | < .001 | 76 | 50-85 | < .001 |
NR | 7 | 24 | -0.2 | −1.2-1.6 | n.s. | 27 | 4-55 | .01 |
Total | 29 | 100 | 2.5 | −1.2-6.9 | < .001 | 71 | 4-91 | < .001 |
Response level . | Frequency . | Increase in hemoglobin level . | Decrease in IgM concentration . | |||||
---|---|---|---|---|---|---|---|---|
n . | % . | Median, g/dL . | Range, g/dL . | P . | Median, % of baseline level . | Range, % of baseline level . | P . | |
CR | 6 | 21 | 4.0 | 0.0-5.4 | < .001 | 81 | 63-91 | < .001 |
PR | 16 | 55 | 3.1 | 2.0-6.9 | < .001 | 76 | 50-85 | < .001 |
NR | 7 | 24 | -0.2 | −1.2-1.6 | n.s. | 27 | 4-55 | .01 |
Total | 29 | 100 | 2.5 | −1.2-6.9 | < .001 | 71 | 4-91 | < .001 |
Two patients with hemolysis without anemia were treated because of disabling circulatory symptoms, which explains the lower range of hemoglobin level increase among the complete responders. N.s. indicates not significant.