Table 2

Response data

Response levelFrequency
Increase in hemoglobin level
Decrease in IgM concentration
n%Median, g/dLRange, g/dLPMedian, % of baseline levelRange, % of baseline levelP
CR 21 4.0 0.0-5.4 < .001 81 63-91 < .001 
PR 16 55 3.1 2.0-6.9 < .001 76 50-85 < .001 
NR 24 -0.2 −1.2-1.6 n.s. 27 4-55 .01 
Total 29 100 2.5 −1.2-6.9 < .001 71 4-91 < .001 
Response levelFrequency
Increase in hemoglobin level
Decrease in IgM concentration
n%Median, g/dLRange, g/dLPMedian, % of baseline levelRange, % of baseline levelP
CR 21 4.0 0.0-5.4 < .001 81 63-91 < .001 
PR 16 55 3.1 2.0-6.9 < .001 76 50-85 < .001 
NR 24 -0.2 −1.2-1.6 n.s. 27 4-55 .01 
Total 29 100 2.5 −1.2-6.9 < .001 71 4-91 < .001 

Two patients with hemolysis without anemia were treated because of disabling circulatory symptoms, which explains the lower range of hemoglobin level increase among the complete responders. N.s. indicates not significant.

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