Multivariate analysis of anti-HLA antibody and CD34 cell dose
| . | CD34 cell dose . | Anti-HLA antibody . | Hazard ratio . | (95%CI) . | P . |
|---|---|---|---|---|---|
| Neutrophil recovery | > 0.85 × 105/kg | ab-negative | 1 | ||
| ab-positive | 0.55 | (0.31-0.98) | .042 | ||
| positive-vs-CB | 0.27 | (0.05-1.44) | .12 | ||
| ≤ 0.85 × 105/kg | ab-negative | 0.59 | (0.46-0.76) | < .0001 | |
| ab-positive | 0.52 | (0.37-0.74) | .0002 | ||
| positive-vs-CB | 0.17 | (0.07-0.42) | .0001 | ||
| Platelet recovery | > 0.85 × 105/kg | ab-negative | 1 | ||
| ab-positive | 0.78 | (0.45-1.36) | .38 | ||
| positive-vs-CB | 0.50 | (0.09-2.92) | .44 | ||
| ≤ 0.85 × 105/kg | ab-negative | 0.76 | (0.57-1.01) | .057 | |
| ab-positive | 0.51 | (0.32-0.82) | .0051 | ||
| positive-vs-CB | 0.19 | (0.06-0.61) | .0049 |
| . | CD34 cell dose . | Anti-HLA antibody . | Hazard ratio . | (95%CI) . | P . |
|---|---|---|---|---|---|
| Neutrophil recovery | > 0.85 × 105/kg | ab-negative | 1 | ||
| ab-positive | 0.55 | (0.31-0.98) | .042 | ||
| positive-vs-CB | 0.27 | (0.05-1.44) | .12 | ||
| ≤ 0.85 × 105/kg | ab-negative | 0.59 | (0.46-0.76) | < .0001 | |
| ab-positive | 0.52 | (0.37-0.74) | .0002 | ||
| positive-vs-CB | 0.17 | (0.07-0.42) | .0001 | ||
| Platelet recovery | > 0.85 × 105/kg | ab-negative | 1 | ||
| ab-positive | 0.78 | (0.45-1.36) | .38 | ||
| positive-vs-CB | 0.50 | (0.09-2.92) | .44 | ||
| ≤ 0.85 × 105/kg | ab-negative | 0.76 | (0.57-1.01) | .057 | |
| ab-positive | 0.51 | (0.32-0.82) | .0051 | ||
| positive-vs-CB | 0.19 | (0.06-0.61) | .0049 |
CI indicates confidence interval; ab-negative, patient does not have anti-HLA antibody; ab-positive, patient has anti-HLA antibody but the CB does not have the corresponding antigen for the antibody specificity; and positive-vs-CB, patient has anti-HLA antibody and the CB has the corresponding antigen for the antibody specificity.