Table 3 Multivariate analysis for TRM,... | American Society of Hematology

Table 3

Multivariate analysis for TRM, relapse, treatment failure, and mortality in adult MDS patients who underwent HLA-identical sibling (MRD) HCT or 8/8 or 7/8 MUD HCT from 2002-2006

	TRM*	P	Relapse†	P	Treatment failure (death or relapse)‡	P	Mortality§	P
	RR (95% CI)	P	RR (95% CI)	P	RR (95% CI)	P	RR (95% CI)	P
8/8 MUD vs MRD	1.43 (1.06-1.95)	.02	0.85 (0.60-1.18)	.33	1.13 (0.91-1.42)	.26	1.24 (0.98-1.56)	.06
7/8 MUD vs MRD	1.80 (1.23-2.63)	.002	1.02 (0.66-1.60)	.91	1.47 (1.10-1.96)	.008	1.62 (1.21-2.17)	.001
7/8 MUD vs 8/8 MUD	1.25 (0.91-1.72)	.16	1.21 (0.81-1.81)	.35	1.29 (1.00-1.66)	.04	1.30 (1.01-1.68)	.03

	TRM*	P	Relapse†	P	Treatment failure (death or relapse)‡	P	Mortality§	P
	RR (95% CI)	P	RR (95% CI)	P	RR (95% CI)	P	RR (95% CI)	P
8/8 MUD vs MRD	1.43 (1.06-1.95)	.02	0.85 (0.60-1.18)	.33	1.13 (0.91-1.42)	.26	1.24 (0.98-1.56)	.06
7/8 MUD vs MRD	1.80 (1.23-2.63)	.002	1.02 (0.66-1.60)	.91	1.47 (1.10-1.96)	.008	1.62 (1.21-2.17)	.001
7/8 MUD vs 8/8 MUD	1.25 (0.91-1.72)	.16	1.21 (0.81-1.81)	.35	1.29 (1.00-1.66)	.04	1.30 (1.01-1.68)	.03

Other significant factors in the multivariate model includes the following:

KPS and female donor into male recipient.

†

Disease status at HCT, IPSS at diagnosis, and conditioning regimen.

‡

KPS and IPSS at diagnosis.

Age, KPS, and IPSS at diagnosis.

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