Table 1

Summary of clinical details of Australian patient samples included in this study

PPRPGRP
Sex, n (%)   NS 
    M 10 (91) 10 (91)  
    F 1 (9) 1 (9%)  
Median age at Dx, mo, (range) 89 (19-178) 86 (19-189) NS 
Median WCC at Dx, ×109/L, (range) 121.50 (15-886) 28.60 (12-273) .028 
Lineage   NS 
    B 5 (45%) 6 (55%)  
    T 6 (55%) 5 (45%)  
Risk category (BFM)    
    High 11 (100%) 0 (0%) < .001 
    Medium 0 (0%) 8 (73%)  
    Standard 0 (0%) 3 (27%)  
Median length of CR1, mo, (range) 23 (2-72) 43 (24-77) .014 
Mean Bim H3K9Ac, (SD) 1.60 (0.81) 3.11 (1.63) .013 
PPRPGRP
Sex, n (%)   NS 
    M 10 (91) 10 (91)  
    F 1 (9) 1 (9%)  
Median age at Dx, mo, (range) 89 (19-178) 86 (19-189) NS 
Median WCC at Dx, ×109/L, (range) 121.50 (15-886) 28.60 (12-273) .028 
Lineage   NS 
    B 5 (45%) 6 (55%)  
    T 6 (55%) 5 (45%)  
Risk category (BFM)    
    High 11 (100%) 0 (0%) < .001 
    Medium 0 (0%) 8 (73%)  
    Standard 0 (0%) 3 (27%)  
Median length of CR1, mo, (range) 23 (2-72) 43 (24-77) .014 
Mean Bim H3K9Ac, (SD) 1.60 (0.81) 3.11 (1.63) .013 

BFM indicates Berlin-Frankfurt-Munster protocol; CR1, complete remission 1; Dx, diagnosis; F, female; M, male; NS, not significant; PGR, prednisolone good responder; PPR, prednisolone poor responder; and WCC, white cell count.

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