Table 3

In vivo efficacy of vorinostat and dexamethasone against ALL-2

Median EFS with range, dLGD, dLog rank value vs control
Control 22.4 (17.8-23.0)   
Vorinostat 23.5 (20.2-35.0) 1.1 0.18 
Dexamethasone 31.5 (20.7-30.4) 9.1 0.012 
Vorinostat + dexamethasone 46.9 (30.0-50.9) 24.5 0.0006 
Median EFS with range, dLGD, dLog rank value vs control
Control 22.4 (17.8-23.0)   
Vorinostat 23.5 (20.2-35.0) 1.1 0.18 
Dexamethasone 31.5 (20.7-30.4) 9.1 0.012 
Vorinostat + dexamethasone 46.9 (30.0-50.9) 24.5 0.0006 

ALL indicates acute lymphoblastic leukemia.

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