Patient information (specimens in final analysis)
| Specimens/characteristic . | Value . |
|---|---|
| Total, N | 172 |
| AML | 108 |
| ALL | 28 |
| CD34+ cells | 21 |
| White blood cells | 15 |
| ALL | |
| Primary diagnosis specimens, n | 28 |
| Mean age, y (range) | 8.7 (1-17) |
| Sex, male/female | 12/6 |
| Mean white blood cells, ×103/μL (range) | 77 (1.7-574) |
| Immunophenotype, n | |
| c-ALL | 17 |
| Pre–B-ALL | 4 |
| Pro–B-ALL | 6 |
| T-ALL | 1 |
| Balanced translocations, n | |
| t(9;22) | 2 |
| t(4;11) | 4 |
| t(12;21) | 3 |
| AML | |
| Specimens, n | |
| Primary diagnosis | 100 |
| Relapse or refractory | 8 |
| Mean age, y (range) | 54 (17-79) |
| Sex, male/female | 65/43 |
| Mean hemoglobin, g/dL (range) | 9.3 (5.2-14.3) |
| Mean platelets, ×103/μL (range) | 60 (7-656) |
| Mean white blood cells, ×103/μL (range) | 61 (0.4-935) |
| Karyotype, n | |
| Normal | 36 |
| Complex karyotype | 17 |
| inv(16) | 11 |
| t(15;17) | 13 |
| t(8;21) | 10 |
| Others/not determined | 21 |
| FLT3-ITD mutation | 18 |
| NPM1 mutation | 10 |
| Specimens/characteristic . | Value . |
|---|---|
| Total, N | 172 |
| AML | 108 |
| ALL | 28 |
| CD34+ cells | 21 |
| White blood cells | 15 |
| ALL | |
| Primary diagnosis specimens, n | 28 |
| Mean age, y (range) | 8.7 (1-17) |
| Sex, male/female | 12/6 |
| Mean white blood cells, ×103/μL (range) | 77 (1.7-574) |
| Immunophenotype, n | |
| c-ALL | 17 |
| Pre–B-ALL | 4 |
| Pro–B-ALL | 6 |
| T-ALL | 1 |
| Balanced translocations, n | |
| t(9;22) | 2 |
| t(4;11) | 4 |
| t(12;21) | 3 |
| AML | |
| Specimens, n | |
| Primary diagnosis | 100 |
| Relapse or refractory | 8 |
| Mean age, y (range) | 54 (17-79) |
| Sex, male/female | 65/43 |
| Mean hemoglobin, g/dL (range) | 9.3 (5.2-14.3) |
| Mean platelets, ×103/μL (range) | 60 (7-656) |
| Mean white blood cells, ×103/μL (range) | 61 (0.4-935) |
| Karyotype, n | |
| Normal | 36 |
| Complex karyotype | 17 |
| inv(16) | 11 |
| t(15;17) | 13 |
| t(8;21) | 10 |
| Others/not determined | 21 |
| FLT3-ITD mutation | 18 |
| NPM1 mutation | 10 |