Table 1

Respiratory mechanics in 34-1-2s-treated BALB/c and SCID mice

BALB/c
SCID
0 minutes60 minutes0 minutes60 minutes
IC/bw, mL/kg 42.8 ± 1.15 40.0 ± 2.25 39.1 ± 4.35 26.8 ± 5.4* 
V, μL 949 ± 555 876 ± 75* 793 ± 12 469 ± 12* 
G, cmH2O/mL 4.30 ± 0.47 4.19 ± 0.28 5.65 ± 1.43 9.03 ± 2.7* 
Rn, cmH2O · s/mL 0.45 ± 0.07 0.40 ± 0.02 50.64 ± 0.07 0.59 ± 0.14 
BALB/c
SCID
0 minutes60 minutes0 minutes60 minutes
IC/bw, mL/kg 42.8 ± 1.15 40.0 ± 2.25 39.1 ± 4.35 26.8 ± 5.4* 
V, μL 949 ± 555 876 ± 75* 793 ± 12 469 ± 12* 
G, cmH2O/mL 4.30 ± 0.47 4.19 ± 0.28 5.65 ± 1.43 9.03 ± 2.7* 
Rn, cmH2O · s/mL 0.45 ± 0.07 0.40 ± 0.02 50.64 ± 0.07 0.59 ± 0.14 

Respiratory mechanics in BALB/c and SCID mice as analyzed by the flexivent technique at baseline (0 minutes) and 60 minutes after induction of TRALI by infusion of 34-1-2s (150 μg). Data from n = 5 each.

*

P < .05 vs BALB/c.

P < .05 vs baseline.

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